Gambro Dialysatoren Gmbh & Co Kg

Gambro Dialysatoren Kg

Gambro Ab

Hans-Dieter Lehmann

Lars-Ake L Larsson

Peter Konstantin

Ruth S Golla

Gerd G Krisam

Biologically active material such as an enzyme is bonded to a carrier containing hydroxyl groups by binding an isocyanate compound to the carrier and bonding the biologically active material to the bound isocyanate compound. Binding of the isocyanate compound to the carrier is achieved with the use of a non-toxic titanium based compound which catalyzes the formation of urethane bonds. The preferred non-toxic based titanium compound is an orthotitanium acid ester such as tetrabutyltitanate.

Method of binding a biologically active material to a carrier containing

A process is disclosed for removing urea from blood wash fluids or blood fluids in which the fluids are treated with an organic solid containing at least one proton-containing secondary substituent group which masks and activates the aldehyde group and the fluids and the solid organic compound are separated.

Process for the removal of urea from blood wash fluids and blood

Polyurethane molding compositions are disclosed which contain diisocyanates and polyols and/or polyurethane prepolymers and sorbic acid or cinnamic as a setting catalyst. A process for preparing such compositions is also disclosed. These compositions give a rapid initial hardening and therefore mold release properties, which contribute to increased production speeds. Moreover, the acids used are physiologically safe, so that the process may be used for the production of objects used in medical science. The acids may also be used in a physiologically safe mixture with a heavy-metal containing catalyst.

Process for the catalytic setting of polyurethane molding compositions

Processes and apparatus for the removal of waste metabolites from metabolite-containing solutions are disclosed. The disclosed processes include alternatively adsorbing and desorbing the metabolites on a pair of adsorbent-containing columns, each column being maintained at a reduced temperature during adsorption and at an elevated temperature during desorption, with the columns being flushed subsequent to desorption and prior to their re-use for adsorption thereon. The disclosed apparatus includes a pair of adsorbent-containing columns, means for alternatively delivering the metabolite containing solution to each of the columns for alternate adsorption and desorption thereon, means for withdrawing the metabolite containing solution from each of the columns, means for alternately flushing the columns subsequent to desorption and prior to adsorption thereon, and means for alternately maintaining the columns at reduced temperatures during adsorption and at elevated temperatures during desorption so that the effectiveness of the adsorbent for adsorption is increased during adsorption at the reduced temperatures. A disposable tube set for use in connection with such a pair of adsorbent containing columns is also disclosed, including a flexible inlet tube including a pair of inlet branches for delivery of the metabolite containing solution to each of the columns, and a flexible outlet tube including a pair of outlet tube branches for connection with the outlet end of each of the columns.

Process and device for the removal of waste metabolites from a solution

Columns for the treatment of a liquid with particulate material are disclosed comprising first and second layers of sheet material in face-to-face contact with each other, an inlet and an outlet located at points between the layers, and welds or the like for joining the layers together along a pair of substantially parallel paths between the inlet and the outlet in order to form an elongated space adapted to be filled with particulate material therebetween. In a preferred embodiment, the aforesaid column comprises a first column portion, and the column includes a second column portion which also includes layers of sheet material in face-to-face contact with each other, an inlet, an outlet, welds for joining the two layers of sheet material together along a pair of substantially parallel paths between the inlet and the outlet so as to form an elongated space adapted to be filled with the particulate material therebetween, and a tubular connector for connecting the outlet from the first column portion with the inlet to the second column portion so that liquid may be fed from the inlet to the first column portion through both column portions to the outlet from the second column portion for contact with the particulate material in both column portions.

Column for the treatment of a liquid by means of a particulate material

A column for removing poisons and/or other undesired substances from a liquid mixture. The column has a mixture of inactive filler particles and active granules positioned therein, with said filler particles being substantially larger than said active granules, (which are selected from adsorbing material and ion-exchanging material). The filler particles are in fixed contact relationship with each other and the active granules completely fill the spaces between the filler particles.

Growing community of inventors

Hechingen, Germany

Hans-Dieter Lehmann