Merck Patent Gesellschaft MIT Beschrankter Haftung

Hans Bardonner

Hartmut Hartner

Arno Basedow

Peter C Schmidt

Hans-Wolfgang Hugenbusch

Friedrich Reiff

Michael Romer

Ernst Felder

Wolfgang Fruhstorfer

Bruno Wollemann

A process for the production of hydroxyamines of the formula I

Process for the preparation of hydroxyamines

A modified sorbitol with improved tableting properties, viz, has a melting point of about 96.degree. C., a bulk density of 0.3-0.6 g/ml, a .gamma.-sorbitol content of at least 90%, a purity of at least 98%, a specific surface area of 0.7-1.5 m.sup.2 /g, a bending strength of at least 7 N/mm.sup.2 at a compressive force of at least 10,000 N, and a friability of less than 1% at a compressive force of at least 10,000 N, can be prepared by obtaining a sorbitol solution by hydrogenation of crystallized glucose at a temperature below 170.degree. C., and spray-drying this solution at a temperature of 140.degree. to 170.degree. C. The sorbitol thus obtained has a water content of less than 1%. The sorbitol is useful for the production of compressed formulations.

Sorbitol, process for its preparation, and use thereof

A process for preparing an N,N-disubstituted p-phenylenediamine of the formula ##STR1## wherein R.sup.1 is alkyl of 1-6 C atoms, R.sup.2 is alkyl of 1-6 C atoms or alkyl of 1-6 C atoms which is substituted by OH, lower alkoxy, a sulfo group or an alkylsulfonamido group and R.sup.3 is hydrogen or lower alkyl

Process for preparing N,N-disubstituted p-phenylenediamine derivatives

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Bad Konig, Germany

Hans Bardonner