Seoul National University

Korea University Research and Business Foundation

Snu Rdb Foundation

Hang-Rae Kim

Young Keun Kim

Youn Sang Kim

Yu Jin Kim

Yoo Sang Jeon

Chang Su Kim

Da-yeon Nam

Jin-Hee Kim

Hyun Mu Shin

Bokyung Kim

A method of preparing an immunological substance detection nanowire complex includes preparing a multilayer nanowire in which a first metal and a second metal are alternately stacked, attaching a polymer, having a carboxyl group and an amine group at both ends of the polymer, to the second metal, attaching a first antibody, treated with a thiol's group, to the first metal of the multilayer nanowire, and attaching a second antibody to the second metal through the carboxyl group of the polymer. The second antibody includes a phosphor.

Multilayer nanowire complex and method of preparing the same

The present disclosure relates to a culture scaffold for promoting differentiation from stem cells or precursor cells into osteoblasts, in which the culture scaffold includes a structure composed of a ridge and a groove, a kit using the culture scaffold, and a method for differentiating stem cells or precursor cells into osteoblasts. The culture scaffold of the present disclosure has an optimal pattern depending on the type of stem cells or precursor cells, thereby improving the osteoblast differentiation potency. In particular, it has a feature of showing excellent osteoblast differentiation potency even if only a small amount of supplementary factors inducing osteoblast differentiation is added. Furthermore, since the osteoblast differentiation potency is not greatly influenced by the change in cell density, it is possible to induce differentiation into osteoblasts without being influenced by the inflammatory environment formed by the inflammatory factors that increase upon cell differentiation. Thus, there is an advantage in that the differentiation efficiency into osteoblasts is high. Accordingly, the culture scaffold of the present disclosure having excellent bone regeneration ability can be utilized in various biomedical and medical fields such as dental implants, artificial joints and trauma fixation devices.

Culture scaffold for enhancing differentiation of osteoblast using pattern

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Seoul, South Korea

Hang-Rae Kim