Biacore Ab

H&aring;kan E Roos

Magnus Malmqvist

Karl Andersson

Mattias Tidare

H&aring;kan Sj&ouml;din

Stefan Sj&ouml;lander

Markku H&auml;m&auml;l&auml;inen

Ralph St&aring;lberg

Surface regeneration of affinity biosensors and characterization of biomolecules associated therewith by multivariate technique employing cocktails of regeneration agents to optimize regeneration of biosensor surface and/or characterize biomolecules associated therewith. Kits and stock solutions for use in the context of this invention, as well as associated computer algorithms are also disclosed.

Surface regeneration of biosensors and characterization of biomolecules associated therewith

Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods permit selective sensitization of the discrete sensing areas, and provide selective contact of the discrete sensing areas with a sample fluid flow. Immobilization of a ligand upon the discrete sensing area, followed by selective contact with an analyte contained within the sample fluid flow, allows analysis by a wide variety of techniques. Sensitized sensing surfaces, and sensor devices and systems are also provided.

Method and device for laminar flow on a sensing surface

Growing community of inventors

Uppsala, Sweden

Håkan E Roos

Growing community of inventors

Uppsala, Sweden

H&aring;kan E Roos

Håkan E Roos