Nova Biomedical Corporation

Other

Sanvita Medical Corporation

Handani Winarta

Chung Chang Young

Xiaohua Cai

Jianhong Pei

Mary M Lauro

Andy Vo

Fung Seto

Thomas Herbert Peterson

Anthony Florindi

Jeffrey C Chien

John Hiti

David H Dicks

Nicole Pouliot

Chin-Chun Chen

Kenneth Gary

A continuous glucose monitoring system and method has an inserter assembly for inserting a sensor through the skin and into subcutaneous tissue where an inserter housing with the sensor remains on the skin after insertion, a sensor housing cover attachable to the sensor housing after insertion where the sensor housing cover has an electronic module and a battery, and an electronic device equipped with wireless communication for communicating with the electronic module of the sensor housing cover assembly, the electronic device configured for receiving input signals from the sensor, converting the input signals to analyte date, displaying the analyte data on a user interface of the electronic device, storing the data for recall, and creating and/or sending reports of the data.

Continuous glucose monitoring system and method

A disposable urea sensor has a laminated body having a fluid sample inlet end and an electrical contact end, a fluid sample inlet, a substantially flat sample chamber in communication between the fluid sample inlet and a vent opening, the sample chamber being adapted to collect a fluid sample through the fluid sample inlet, a working electrode and a reference electrode within the sample chamber, and a reagent matrix disposed on the working electrode wherein the reagent matrix contains urease.

Disposable urea sensor and system for determining creatinine and urea nitrogen-to-creatinine ratio in a single device

An improved biosensor having at least a first working electrode and a first electrode material disposed on the first working electrode. The first electrode material is a mixture made by combining at least one enzyme where the at least one enzyme is a capable of reacting with the analyte to be measured, a redox mediator capable of reacting with a product of an enzymatic reaction or a series of enzymatic reactions involving the at least one enzyme, a peroxidase capable of catalyzing a reaction involving the redox mediator where the redox mediator is oxidized, a binder and a surfactant.

Biosensor with peroxidase enzyme

Biosensor and method

A disposable electrode strip for testing a fluid sample including a laminated strip with a first and second end, a vent, an open path for receiving a fluid sample of less than one microliter beginning from the first end and connecting to the vent, a working electrode, a reference electrode and a pseudo-working electrode embedded in the laminated strip within the open path and proximate to the first end, a reagent matrix coextensive within the open path and covering the three electrodes, and conductive contacts located at the second end of the laminated strip.

Disposable sub-microliter volume biosensor with enhanced sample inlet

A disposable biosensor for testing a fluid sample including a laminated strip with a first and second end, a reference electrode embedded in the laminated strip proximate to the first end, at least one working electrode embedded in the laminated strip proximate to the first end and the reference electrode, an open path for receiving a fluid sample beginning from the first end and connecting to a vent spaced from the first end, the open path being sufficiently long to expose the reference electrode and the working electrode to the fluid sample, and conductive contacts located at the second end of the laminated strip. The laminated strip has a base layer with a conductive coating, a reagent holding layer, a channel forming layer and a cover having an inlet notch at the first end. The working electrode contains a reagent having an enzyme.

Disposable sensor with enhanced sample port inlet

A disposable electrode strip for testing a fluid sample including a laminated strip with a first and second end, a reference electrode embedded in the laminated strip proximate to the first end, at least two working electrodes embedded in the laminated strip proximate to the first end and the reference electrode, an open path for receiving a fluid sample beginning from the first end and being sufficiently long to expose the reference electrode and the working electrodes to the fluid sample, and conductive contacts located at the second end of the laminated strip. The laminated strip has a base layer with a conductive coating, a reagent holding layer, a channel forming layer and a cover. One of the working electrodes contains a reagent substantially similar to the reagent of the reference electrode and a second working electrode contains a reagent having an enzyme.

Disposable sensor and method of making

Disposable sub-microliter volume sensor and method of making

An electrochemical sensor with a gelled membrane for prolonging the useful life of an ion-selective electrode. The gelled membrane is a hydrophilic membrane having a specially-formulated gel layer coated on one side. The gel-coated side of the gelled membrane is in intimate contact with the ion-selective membrane and separates the ion-selective membrane from the test samples and the calibration and cleaning fluids. The gelled membrane is a semi-permeable barrier which allows passage of the species to be measured while inhibiting the passage of surfactant and proteinaceous material into the polymeric ion-selective membrane.

Electrochemical sensor with gelled membrane and method of making

Disclosed is a method of assaying a high concentration of a substance in a liquid sample with a polarographic cell. The cell contains an electrode assembly that includes a reference electrode and a hydrogen peroxide sensor electrode having a laminated membrane covering the liquid sample contacting face of the sensor electrode. The laminated membrane includes an outer membrane permeable to the substance and oxygen, an inner membrane permeable to hydrogen peroxide and located adjacent the face of the sensor electrode, and an enzyme layer between the inner and outer membrane; the enzyme in the enzyme layer can oxidize the substance to generate hydrogen peroxide. The method includes contacting the outer membrane with the liquid sample; permitting the substance and oxygen in the liquid sample to pass through the outer membrane to contact the enzyme layer so that where the substance is oxidized to generate hydrogen peroxide; permitting the generated hydrogen peroxide to pass through the inner membrane to contact the sensor electrode; and ensuring that the supply of oxygen in the enzyme layer relative to the supply of glucose is sufficient to produce an equilibrium concentration of hydrogen peroxide, which generates a steady state response at the sensor electrode proportional to the concentration of the substance in the liquid sample.

Method of using enzyme electrode

An electrode assembly for polarographic assay of glucose in solution having a laminated membrane, the outer membrane being from 1 to 20 .mu.m thick and having a pore size of 10 to 125 .ANG., the inner membrane having a thickness of 2 to 4 .mu.m, and bonded to the outer membrane with immobilized glucose oxidase. Rapid assays are carried out by measuring the current difference before equilibrium is attained and at least 5 seconds after initial contact of sample with the outer membrane.

Growing community of inventors

Nashua, NH, United States of America

Handani Winarta