Yukong Limited

Han Dong Il

Choi Yong Moon

Kim Hyung Cheol

There is disclosed 3-N-substituted thiocarbamoyl-2-phenyl-1,3-propanediol carbamate, represented by the following structural formula I, that is very effective for prophylaxis and treatment of central nervous system disorders including nervous muscular pain, epilepsy and cerebral apoplexy: ##STR1## wherein R.sub.1 and R.sub.2 may be the same or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl containing 1 to 8 carbon atoms and 5 to 7-membered aliphatic cyclic compound which may comprise two or less nitrogen or oxygen atoms directly unconnected, with a proviso that R.sub.1 and R.sub.2 both should not be hydrogen and the total number of carbon atoms of R.sub.1 and R.sub.2 ranges from 1 to 16.

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Taejon, South Korea

Han Dong Il