University of California

Hamid R Djalilian

Mark Bachman

Peyton Paulick

Mark Merlo

Harrison W Lin

Arash Kheradvar

Fan-Gang Zeng

Ronald Sahyouni

An oral irrigator system having an ergonomic casing with a pliable nozzle assembly, and coupled to a detachable and refillable fluid reservoir. The ergonomic casing contains a power source and a pump mechanism. The detachable nozzle head delivers a pulsating jet of fluid with adjustable speed into the oropharyngeal cavity. When the system is turned on, the rechargeable battery activates the diaphragm pump to draw fluid from the reservoir using a fluid pipe and delivers the fluid to the tip of the nozzle head.

System for irrigating the upper aerodigestive tract and neighboring areas

The disclosure provides for a combination therapy comprising different classes of medications for the treatment of tinnitus and other medical conditions, and methods of treatment thereof.

Combination therapy for the treatment of tinnitus and other medical conditions

An electrical stimulation system that provides for transtympanic stimulation of the inner ear that can be used for safely and effectively treating tinnitus. The electrical stimulation system of the present invention may be fully implantable or partially implantable. The system features an electrode placed on the round window membrane. An external portion provides the power to the electrode, which can stimulate the inner ear via the round window as needed by the patient. The present invention also features methods of treating tinnitus using the electrical stimulation system described herein.

Methods and systems for treating tinnitus with transtympanic electrical stimulation

Disclosed herein is a method of treating a disease, comprising: (a) implanting an array of electrodes on one or more targeted nerves and/or targeted muscles; and (b) treating the disease by selectively stimulating the one or more targeted nerves and/or targeted muscles through electrical pulses delivered from the array. Also disclosed herein is a device, comprising a plurality of electrodes that have the capacity to be inserted in or around a facial nerve. Further disclosed herein is a method of treating facial paralysis and/or damage in a subject, comprising: (a) detecting the level of contraction of individual muscles on a healthy, non-paralyzed side of the face of the subject; and (b) treating facial paralysis by a direct targeted stimulation of the corresponding muscles or nerve fibers on a paralyzed side of the face of the subject. Also disclosed herein is a method of treating synkinesis, comprising: (a) implanting an array of electrodes on one or more targeted nerves and/or targeted muscles; and (b) selectively suppressing the one or more targeted nerves and/or targeted muscles through electrical pulses delivered from the array.

Nerve stimulation device for treating or reducing paralysis

A hearing aid apparatus is provided. In one embodiment, a system and method are provided for using a tympanostomy tube as a platform for driving the middle ear. The system and method may employ a mechanical interface for driving the middle ear. In another embodiment, a hearing aid apparatus includes a direct-drive hearing device (DHD) having a silicone mold on one end, where the silicone mold has an attached magnet; and a tympanostomy tube with a ferromagnetic cap, where the tympanostomy tube is insertable into a tympanic membrane. The DHD is configured for insertion in an ear canal such that the magnet attached to the silicone mold is in contact with the ferromagnetic cap of the tympanostomy tube.

Direct-drive acoustic amplification using a tympanostomy tube

A device and methods are provided for a hearing device. In one embodiment, a hearing device includes a microphone to receive sound, an interactive tip and actuator. The actuator can include an actuator element and preload force element to place the interactive tip in contact with a portion of an ear. The hearing device includes circuitry coupled to the microphone and actuator, the circuitry configured to process sound received by the microphone and drive the actuator based on processed sound, wherein the actuator drives the interactive tip relative to a portion of the ear based on one or more signals received from the circuitry.

Growing community of inventors

Orange, CA, United States of America

Hamid R Djalilian