Zimmer Knee Creations, Inc.

Warsaw Orthopedic, Inc.

Sdgi Holdings, Inc.

Danek Medical

K2m, Inc.

Hallett H Mathews

Peter F Sharkey

Charles F Leinberry

David L Nichols

Marc R Viscogliosi

Lukas G Eisermann

Tai Friesem

Jean-Charles Lehuec

Eddie F Ray, Iii

Mingyan Liu

Bradley T Estes

Loic Josse

Rudolf Bertagnoli

Richard W Woods

Richard D Guyer

Jeffrey Zhang

Gordon D Donald

Jean-Jaques Abitol

Bruce Mathern

Charles S Theofolis

Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.

Subchondral treatment of joint pain of the spine

A prosthetic device for insertion into a spondylosed intervertebral space is provided. The prosthetic device includes a first component having a first flange for longitudinally engaging a first vertebra during longitudinal insertion therein, and a second component having a second flange for longitudinally engaging a second vertebra during longitudinal insertion therein. One of the first and second components comprises a projection and the other of the first and second components comprises a recess, the projection and recess being adapted to engage one another. One of the projection and the recess are offset relative to the other of the projection and the recess to accommodate the spondylosed relationship between the first and second vertebrae.

Spinal disc prosthesis and associated methods

Provided is a system and devices for use in the treatment and repair of moveable skeletal joints in the body of a subject. In particular, the present invention relates to the complete or partial posterior modular disc replacement of damaged or diseased fibrocartilage intervertebral discs in a subject wherein the replacement disc is capable of rotation and translation articulation.

Posterior modular disc replacement system

Methods and instruments for preparing a disc space and for forming interbody devices therein are provided. The instruments include distractors having enlargeable portions positionable in the disc space for distracting the disc space. The enlargeable portions can also provide form about or against which an interbody device of a first material is placed. A second material may be placed in the disc space in the space previously occupied by the distractors.

Methods and devices for interbody spinal stabilization

Articular disc prosthesis and method for treating spondylolisthesis

An instrument for separating adjacent vertebrae includes a handle assembly and a distal portion at a distal end of the handle assembly. The distal portion includes first and second members movable from an unexpanded configuration for insertion in the disc space toward an expanded configuration to separate the vertebrae. A cutting member of a cutting instrument can be guided by the instrument to prepare the vertebrae for engagement with an implant.

Instrumentation and methods for preparation of an intervertebral space

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Richmond, VA, United States of America

Hallett H Mathews