Secretary, Department of Atomic Energy

Haldhar Dev Sarma

Vikram Prakash Gota

Santosh Kumar Sandur

Raghavendra Shridhar Patwardhan

Subrata Chattopadhyay

Rahul Checker

Deepak Sharma

Jayakumar Sundarraj

Dharmendra K Maurya

Maikho Thoh

Vikram P Gota

A method of treatment of disease condition resulting from deficiency of hematopoietic stem and progenitor cells and/or epidermal stem cells in skin comprising: administering to the subject suffering from said disease conditions, an effective amount of Jack bean lectin or a pharmaceutically acceptable salt thereof for increasing the abundance of hematopoietic stem cells and progenitor cells in bone marrow and/or epidermal stem cells in skin in vivo. Method of treating said conditions in a subject involves administering a single injection of lectin in a dose range of 0.5-2.0 mg/kg body weight to mouse leading to 2.815 to 3.55 fold increase in the abundance of epidermal stem cells in skin and a dose range of 8.0-10.0 mg/Kg body weight to a mouse leading to 2.36 to 6.67-fold increase in the abundance of hematopoietic stem and progenitor cells in bone marrow.

Use of jack bean lectin for increasing the abundance of hematopoietic stem cells and progenitor cells in bone marrow and/or epidermal stem cells in skin in vivo

Growing community of inventors

Mumbai, India

Haldhar Dev Sarma