Huawei Technologies Co., Limited

Jiangsu Nuo-beta Pharmaceutical Technology Co. Ltd.

Haiyan Liu

Xiao Xun Zhang

Fude Huang

Wenan Wang

Jun Xu

Qun Yu

Tong Zhu

Yang He

Le Zhang

Yudong Zhou

Wanguo Wei

Lixiang Jiang

Huibin Chen

Xiao Zhang

An encapsulation structure of a power module is disclosed in this application, which includes a power module and a liquid cooler. The power module includes a power module body, a metal baseplate, and heat dissipation finned tubes. A front side of the metal baseplate is connected to the power module body, and a back side of the metal baseplate is connected to the heat dissipation finned tubes. The metal baseplate has a protrusion part protruding. There are a plurality of grooves on a fluid pipe of the liquid cooler, a cavity exists between two adjacent grooves of the plurality of grooves, and the cavity is configured to communicate the two adjacent grooves. The power module body is lapped on the groove, a back side of the protrusion part is in contact with an edge surface of the groove, and the heat dissipation finned tubes are placed in the groove.

Encapsulation structure and encapsulation method of power module

The use of a genetic method to down-regulate RBO/EFR3/EFR3A/EFR3B proteins, TTC7 protein or PI4KIII&#x3b1; enzyme protein which interacts with RBO/EFR3/EFR3A/EFR3B proteins and TTC7 protein, or the use of a drug to inhibit PI4KIII&#x3b1; protein kinase activity reduces the accumulation of A&#x3b2;within neurons and age-dependent synaptic transmission failure and other obstacles in a fruit fly AD model, and obtains an effect of improving the learning and memory abilities of AD model mice. Provided is a method for using an RBO/EFR3/EFR3A/EFR3B inhibitor, a TTC7 inhibitor and a PI4KIII&#x3b1; inhibitor to treat Alzheimer's disease. Also provided is a method for screening a drug treating Alzheimer's disease by whether A&#x3b2; secretion by nerve cells is promoted or not.

Application of PI4KIIIA protein and related membrane protein complex in treating alzheimer's disease

Disclosed is the use of genetic means or a related inhibitor to inhibit and down-regulate the amount of PI4KIII&#x3b1; protein, RBO/EFR3/EFR3A/EFR3B membrane proteins, TTC7 protein and membrane protein complexes formed by said proteins, or related enzyme activity to promote A&#x3b2; secretion by neuronal cells, reduce A&#x3b2; accumulation within neurons, and thereby reduce AD model fruit fly and mouse nerve dysfunction.

Method for screening drug and therapeutic targets used for treating Alzheimer's disease

A data processing method and apparatus are provided. A system includes a CPU pool and a storage pool, a mapper node and a reducer node respectively run on different CPUs in the CPU pool, and a remote storage area shared by the mapper node and the reducer node is delimited in the storage pool. In this method, the mapper node executes a map task, and stores a data segment obtained by executing the map task, into the remote storage area; and the reducer node directly obtains a data segment to be processed by the reducer node from the remote storage area, and executes a reduce task on the data segment. The method omits some actions in the prior art, and shortens a time for executing the Map/Reduce task.

Data processing method and apparatus, and system

Growing community of inventors

Shanghai, China

Haiyan Liu