Purdue Research Foundation

Endocyte, Inc.

Seattle Children's Hospital

Haiyan Chu

Philip Stewart Low

Christopher Paul Leamon

Yingjuan June Lu

Yong Gu Lee

Leroy W Wheeler, Ii

Michael C Jensen

James Matthaei

Richard Messmann

Navin Robert Charles Pinto

Julie Ruggieri Park

Leroy W Wheeler Ii

The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.

Methods of use for CAR T cells

The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.

Sequencing method for CAR T cell therapy

Cytotoxic lymphocytes expressing chimeric antigen receptors (CAR) that target and bind small conjugate molecules (SCM) are disclosed, as well as methods of using the cells and the SCMs in the treatment of cancer.

Chimeric antigen receptor-expressing T cells as anti-cancer therapeutics

The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.

Methods and compositions for car T cell therapy

Compositions and methods for CAR T cell therapy

Growing community of inventors

West Lafayette, IN, United States of America

Haiyan Chu