Shanghai Ennovabio Pharmaceuticals Co., Ltd.

Other

Ennovabio (zhejiang) Pharmaceuticals Co., Ltd.

Guangdong Zhongsheng Pharmaceutical Co., Ltd

Haixia Zhao

Lei Jiang

Shengyang Liu

Xiaoping Xie

Zhiyong Feng

Shuhui Chen

Jian Li

Xing Liu

Yuan Xu

Ke Shang

Jianwen Deng

Xueli Xu

Zhi Qiao

Guoping Hu

Jianhua Zhang

Zhengxia Chen

Chaofeng Long

Xiaoxin Chen

Zhuowei Liu

Meibi Dai

Mingwei Zheng

Yikai Wang

Jianyong Shou

Danyi Wu

Xudong Mao

Yang Zhang

The present invention provides preparation of a semicarbazide-sensitive amine oxidase inhibitor and use thereof. In particular, disclosed in the present invention are a compound as represented by formula I, or a stereoisomer or a racemate or a pharmaceutically acceptable salt of the compound. Also disclosed in the present invention is that the compound can inhibit semicarbazide-sensitive amine oxidase.

Preparation of semicarbazide-sensitive amine oxidase inhibitor and use thereof

Provided are a preparation of semicarbazide-sensitive amine oxidase inhibitor and the use thereof. In particular, disclosed are a compound as shown in formula I, or a stereoisomer or racemate or pharmaceutically acceptable salt thereof. Also disclosed is that the above-mentioned compound can inhibit semicarbazide-sensitive amine oxidase.

Preparation of seimicarbazide-sensitive amine oxidase inhibitor and use thereof

Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.

Aromatic heterocyclic compound with kinase inhibitory activity

Provided are a class of compounds as shown in formula (I) as FGFR4 inhibitors, and pharmaceutically acceptable salts thereof, preparation methods therefor and the use thereof in the preparation of drugs for treating FGFR4-related diseases. 

FGFR4 inhibitor and preparation method and use thereof

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Shanghai, China

Haixia Zhao