Hoffmann-la Roche Inc.

F. Hoffmann-la Roche Ag

Haixia Liu

Wei Zhu

Guolong Wu

Hong Shen

Taishan Hu

Lei Guo

Xianfeng Lin

Weixing Zhang

Zhisen Zhang

Buyu Kou

Mingwei Zhou

Buelent Kocer

Yimin Hu

Zongxing Qiu

Hongying Yun

Zhiwei Zhang

Fabian Dey

Alexander Mayweg

Lisha Wang

Yongfu Liu

Chao Li

Ge Zhu

Guozhi Tang

Houguang Shi

Gangqin Li

Song Feng

Dongdong Chen

Dan Zhao

Shixiang Yan

Isabel Najera

Jianguo Chen

Xiaoqing Wang

Yafei Liu

Zheng Zhou

Lue Dai

Hong Sheng

Junwei Xi

John G Cumming

Virginie Sandrin

Linuo Zhu

Alexander V Mayweg

The present invention relates to compounds of formula (I), wherein R, R, Rand Rare as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Pyrazolopyridine compounds for the treatment of autoimmune disease

The present invention relates to compounds of formula (Ib), wherein Rto R, M and L are as described herein, and their pharmaceutically acceptable salt, enantiomers and diastereomers thereof, and compositions including the compounds and methods of using the compounds.

Tricyclic compounds for the treatment of cancer

The present invention relates to compounds of formula (I), ab (I), wherein R1 to R3 and L are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Heteroaryl heterocyclyl compounds for the treatment of autoimmune disease

The present invention relates to compounds of the formula (I), 

Pyrazine compounds for the treatment of hepatitis B infection

The present invention relates to compounds of formula (I): 

Pyridazinone-based broad spectrum anti-influenza inhibitors

Carboxy tetrahydropyrazolopyrazine compounds for the treatment of infectious diseases

The present invention relates to compounds of formula (I), wherein R, Rand Rare as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Oxathiolane carboxylic acids and derivatives for the treatment and prophylaxis of virus infection

The present invention relates to compounds of formula (I), wherein R, R, R, R, Rand Rare as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

Compounds for the treatment of infectious diseases

The invention provides novel compounds having the general formula: wherein R, R, R, R, R, M and X are as described herein, compositions including the compounds and methods of using the compounds.

4-methyl-dihydropyrimidines for the treatment and prophylaxis of Hepatitis B virus infection

The invention provides novel compounds having the general formula: wherein R, R, Rand Rare as defined in the description and in the claims, as well as or pharmaceutically acceptable salts, or tautomerism isomers, or enantiomers, or diastereomers thereof. The invention also contains compositions including the compounds and methods of using the compounds.

6-bridged heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis B virus infection

The invention provides novel compounds having the general formula: wherein R, R, R, Rand A are as described herein, compositions including the compounds and methods of using the compounds.

6-amino acid heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis B virus infection

Growing community of inventors

Shanghai, China

Haixia Liu