Microsoft Technology Licensing, LLC

Nokia Corporation

Cansbio (beijing) Biotechnology Co., Ltd.

Haitao Wu

Yongguang Zhang

Chuanxiong Guo

Kun Tan

Songwu Lu

Jian Ma

Dan Li

Danfeng Zhang

Yunfeng Shi

Guohan Lv

Lihua Yuan

Shiduan Cheng

Shipeng Li

Qian Zhang

Yongqiang Xiong

Guohan Lu

Keping Long

Changqing Xia

Yixian Guo

Suigui Wan

Qian Wang

Dongmei Zhang

Lei Shi

Wenwu Zhu

Liang Sun

David A Maltz

Kai Chen

Jun Hong Zhao

Yunxin Liu

Fan Yang

Shi Lei

Runtong Zhang

Yuehui Jin

Huihua Le

Techniques are described for balancing traffic load for networks configured in multi-rooted tree topologies, in the presence of link failures. Maximum flows (through minimum cuts) are calculated for subgraphs that incorporate effective link capacities on links between source and destination nodes. Effective link capacities may be determined that take into account link failures, as well as sharing of current available link capacities by multiple nodes. Traffic is balanced while simultaneously fully utilizing available link capacities, even available link capacities on partially failed links (e.g., partially failed Link Aggregation Groups (LAGs)).

Fault tolerant and load balanced routing

In some cases, a network monitoring system may determine an operating or health condition of a node or connection link in a network (e.g., a datacenter network) by preparing an encapsulated data packet according to a tunneling protocol. Depending on a result of routing the encapsulated data packet, the network monitoring system determines whether the node or connection link is functioning normally or is experiencing an issue such as overloading or malfunctioning.

Fine-grained network monitoring

The present invention pertains to immunology, biomedicine field, specifically relates to a method for prevention or treatment of one or more of diseases relevant to the protein in the protein-cell conjugate, malignant tumors, infectious diseases caused by pathogenic microorganisms and autoimmune diseases. The method includes a step of administering to a subject in such need a prophylactically or therapeutically effective amount of a protein-cell conjugate, the said protein-cell conjugate is a conjugate formed by covalently linking a protein and a cell to a linker, respectively; the cell has free sulfhydryl groups distributed on its surface, when the cell is not linked to the linker; the linker is derived from a bifunctional cross-linking agent, and the bifunctional cross-linking agent comprises both a group capable of reacting with an amino group and a group capable of reacting with a sulfhydryl group.

Method for prevention or treatment of one or more of diseases relevant to the protein in the protein-cell conjugate, malignant tumors, infectious diseases caused by pathogenic microorganisms and autoimmune diseases

Disclosed are systems and methods for network architecture that is a server-centric network architectural design.

Server-centric high performance network architecture for modular data centers

The present invention pertains to immunology, biomedicine field, specifically relates to a protein-cell conjugate, which is characterized in that the protein and the cell are coupled via a bifunctional cross-linking agent. The present invention further relates to a preparation method and uses of the protein-cell conjugate. The protein-cell conjugate of the present invention can be used for prevention or treatment of many diseases, such as malignant tumors, infectious diseases and autoimmune diseases.

Protein-cell conjugate, preparation method and use thereof

This application describes routing packets from a source server to a plurality of ports of a switch. The switch is programmed by the control server and is used to direct incoming data packets to one or more ports of the switch in a manner that reduces congestion of incoming data packets to a destination server. Further, the control server queries congestion information from the switch, and then sends congestion notification back to the source server to either increase or decrease the amount of data being sent to the destination server.

Programmable and high performance switch for data center networks

A system, method or computer readable medium to provide efficient congestion notification is described herein. In various embodiments, a packet is received at an intermediate node of one or more data center networks. A current queue length at the intermediate node is determined. A threshold value for the current queue length is tuned by dynamically computing an upper bound and a lower bound based at least in part on the network. The packet is marked to indicate possible congestion in the one or more data center networks when the current queue length exceeds the threshold value. In some embodiments, the packet is marked when it is being de-queued. In a further embodiment, Flexible Initial Packet Size (FIPS) may be utilized to improve the efficiency of the tuning.

Tuning congestion notification for data center networks

Methods and systems for handing off a wireless client between access points wherein the scanning for access points is decoupled from the handing off, thus reducing the delay in handing off. Channel scan delay may be eliminated or reduced in some embodiments by scanning early (prior to actual handoff) and interleaving the channel scan with ongoing traffic in a non-intrusive way. A smart handoff trigger may be used in some embodiments that covers both uplink and downlink quality, and addresses link asymmetry problems. The methods or systems may be implemented in some embodiments in a software-only client-only solution without the need to modify the networks themselves or their access points.

Decoupling scanning from handoff for reduced delay over wireless LAN

Implementations are described for controlling, avoiding, and/or minimizing incast congestion in a network. In various embodiments, the network may be a data center network, which may include one or more senders and a receiver that transmit data across the network using Transmission Control Protocol. The receiver may be associated with a receive window that may determine amount of data that may be received by the receiver at a single time. Moreover, a size of the receive window may be adjusted based at least in part on an available bandwidth of the receiver. As a result of an increase or decrease in the receive window, the one or more senders may not be constrained in transmitting data to the receiver and incast congestion at the receiver may be reduced and/or avoided.

Incast congestion control in a network

This application describes a system and method for auto configuring data center networks. The networks include a plurality of electronic devices that may include switches, servers, routers, or any other device that may be used in a data center network. Graph theory is applied to the arrangement of the network devices to determine if the intended design of the data network matches the actual implementation of the network. This may be achieved by resolving the blueprint graph with the physical graph to determine if they are isomorphic. Also, the isomorphic techniques may be used to detect miswirings in the network that do not cause a node degree change for any of the network components.

Generic and automatic address configuration for data center networks

A method and system for providing a multi-level interconnection network is provided. A multi-level interconnection network comprises basic cells that are aggregated into higher level cells at each level of the network. At the first level, the basic cells are aggregated into first level cells. Each first level cell is an aggregation of a number of basic cells that is one more than the number of devices in a basic cell. The basic cells of a first level cell are fully connected; that is, each basic cell has a first level link or connection to each other basic cell. In a first level cell, each device of a basic cell has a first level link to each other basic cell. The multi-level interconnection network has higher level cells that are aggregations of lower level cells in a similar manner.

Multi-level interconnection network

A hybrid Butterfly Cube ('BCube') architecture is described herein. The BCube architecture is a server-centric network architectural design, and includes a plurality of servers. Each of the plurality of servers may have multiple network ports and serve not only as an end host, but also an intermediate relay node for other servers. The BCube architecture further includes a plurality of switches which are arranged in multiple levels. Each switch has a certain number of network ports for connecting to the servers. The BCube architecture provides multiple parallel paths between any two servers. A packet source routing protocol and a BCube source routing (BSR) protocol are used to determine which path is used for routing a packet between any two servers.

Hybrid butterfly cube architecture for modular data centers

Growing community of inventors

Beijing, China

Haitao Wu