Medtronic, Inc.

Chinese Academy of Sciences

Haining Na

Jing Chen

Suping Lyu

Xiangji Chen

Jin Zhu

XiangJi Chen

Xiaoqing Liu

Jinggang Wang

Disclosed is a segmented thermoplastic elastomer that can be a polyurethane, polyurea, or polyurethane-urea comprising soft segments and hard segments, wherein the soft segments are made of polyolefin diols or polyolefin diamine that may have 0 to 1000 carbon atoms in the main chain, wherein each carbon atom in the main chain may have 0 to 2 side chains and each side chain may have 0 to 30 carbon atoms, the hard segment is made of a diisocyante and a chain extender, the hard segments make up 10-60% of the elastomer and the soft segments make up the rest, the number-average molecular weight of the elastomer is 5&#xd7;10-1000&#xd7;10g/mol, the ultimate elongation of the elastomer is 100-1000%, the Young's modulus is 1 to 3,000 MPa, and the ultimate tensile strength is 10-100 MPa. Also disclosed are a method for preparing the segmented thermoplastic elastomer and use of segmented thermoplastic elastomer.

Elastomer, method for preparation thereof, and use thereof

A medical device, a method for preparation thereof, and use thereof are provided. The medical device comprises a thermoplastic elastomer that is composed of soft segments and hard segments. The method for preparing a medical device comprising a thermoplastic elastomer, comprises forming the thermoplastic elastomer into tubing or other shapes via extrusion, molding, or coating, assembling the tubing or other shapes with other parts including: cables, coils, coated cables, or coated coils, and bonding the tubing, cables, or coils with other components including: other tubing components, cables, coils, sleeves, electrical pulse generator, defibrillation shock generator, electrodes, sensors, or drug release components. The medical device is used for correcting cardiac rhythm, defibrillating, assisting hearts, sensing, stimulating neurological systems, gastrointestinal system, or skeletomuscular tissues or organs.

Medical device with a tubular portion comprising a thermoplastic elastomer with soft and hard segments, method for preparation thereof, and use thereof

Disclosed is a method for preparing a 2,5-disubstituted furan compound. The 2,5-disubstituted furan compound is prepared in a simple, convenient and highly efficient way by reacting 2,3-dicarboxylic anhydride-7-oxabicyclo[2.2.1]hept-5-ene and/or furan with an acylating reagent and/or an alkylating reagent. The preparation method is simple and efficient, has a short process and less by-products, and the 2,5-disubstituted furan compound prepared by using the method has a high purity, and can satisfy the requirements for being used as a raw material for engineering plastics, such as high-performance polyesters, epoxy resins, polyamides, polyurethanes and the like, and as a chemical raw material and a pharmaceutical intermediate raw material.

Method for preparing 2,5-disubstituted furan compound

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Zhejiang, China

Haining Na