Genzyme Corporation

Becton Dickinson and Company Limited

Biogen Ma Inc.

Baxter International Inc.

Sanofi

Baxter Healthcare Sa

Haiming Wu

Richard A Cronenberg

Danial Paul Ferreira

Alexander Hee-Hanson

Robert Wilson

Thomas Lever

Michael Parrott

Michael Vincent Quinn

Iskandar Vasiev

Adam Christopher Nightingale

Richard E Cronenberg

Tom Alan Oakley

Thomas Mark Kemp

William S Hurst

Craig T Flanagan

Joel John Williams

Kiara May-Leen Taylor

Tom Lever

Dan Ferreira

Lien-Lung Sheu

Matthew Christopher Latham

Thomas A Block

Craig Nelson

Danial P Ferreira, I

A hold assistance device for use with a medicament delivery device is described. The hold assistance device includes: a housing configured to be coupled to a medicament delivery device; a chamber for containing air, the chamber having a proximal end and a distal end; and a piston movable within the chamber between the proximal and distal ends of the chamber, wherein the piston is arrangeable in an activated position inside the chamber in which the piston is arranged proximate to the proximal end of the chamber such that the chamber is at least partially evacuated of air and movement of the piston towards the distal end of the chamber is resisted by a vacuum force.

Hold assistance device for use with a medicament delivery device

A medicament delivery device is described. The medicament delivery device includes a proximal end and a distal end defining a longitudinal axis; a body; and a button arranged at the proximal end and configured to actuate the medicament delivery device. The medicament delivery device further includes a lock ring configured to rotate relative to the body about the longitudinal axis between a first position in which the button is not permitted to move along the longitudinal axis relative to the body, and a second position in which the button is permitted to move along the longitudinal axis relative to the body; a plurality of first indication elements circumferentially spaced around a first portion of the medicament delivery device; and a plurality of second indication elements circumferentially spaced around a second portion of the medicament delivery device.

Medicament delivery device

The application relates to a lock ring for a medicament delivery device. The lock ring comprises a hollow main body formed from a plurality of circumferentially extending portions. Each portion is defined between tool split lines defining circumferential ends of the portions. Each circumferential end of a portion is connected to an adjacent portion along a tool split line. The main body comprises a plurality of bearing elements configured to contact a body of a medicament delivery device. Each of the plurality of bearing elements is configured to form a low friction rotation interface. At least one of the plurality of bearing elements is formed proximate to one of the circumferential ends of a portion of the main body.

Lock ring for a medicament delivery device

A medicament delivery device for injecting medicament which has a body having a proximal end and a distal end, a needle for injecting medicament and an actuation member which is movable relative to the body. The actuation member is movable from a first position to a second position and movable from the second position to a dispensing position for dispensing medicament from the needle. The second position is proximal of the first position. The medicament delivery device further has a cap which is removably attached to the medicament delivery device. The cap has a portion configured to prevent movement of the actuation member from the first position to the second position when the cap is attached to the medicament delivery device.

A medicament delivery device is described. The device includes a body comprising a proximal end and a distal end; a needle for injecting medicament; an actuation member moveable relative to the body for actuating the device; a lock ring configured to rotate relative to the body between a first position in which the actuation member is not permitted to move relative to the body, and a second position in which the actuation member is permitted to move relative to the body; and a cap arrangeable in a capped position in which the cap abuts with and conceals the distal end of the body to conceal the needle; wherein when the cap is in the capped position the lock ring is in a first state in which the lock ring is in the first position and is not permitted to rotate towards the second position; and wherein moving the cap in a distal direction away from the distal end of the body along the longitudinal axis away from the capped position causes the lock ring to be in a second state in which the lock ring is permitted to rotate from the first position towards the second position.

A hold assistance device for use with a medicament delivery device is described. The hold assistance device includes: a first support configured to be fixedly coupled to a main body of a medicament delivery device, wherein the first support comprises a first attraction component; and a second support moveable relative to the first support between an initial position and a hold position and configured to be fixedly coupled to a needle cover of the medicament delivery device, wherein the second support includes a second attraction component, and wherein at least one of the first attraction component and the second attraction component is a magnet, and the other of the first attraction component and the second attraction component is a magnet or a ferromagnetic material; and wherein movement of the second support towards the hold position moves the second attraction component towards the first attraction component.

Hold assistance device

A damping device for a medicament delivery device, comprising: a generally cylindrical first collar; a housing comprising a generally annular cavity configured to receive at least a portion of the first collar; wherein the first collar is configured to be rotatable relative to the housing about a central longitudinal axis of the damping device, and wherein the cavity is configured to contain a fluid for impeding rotational movement of the first collar relative to the housing; and a sealing arrangement configured to fluidly seal an interface between the housing and the first collar.

Damping device for a medicament delivery device

A fluid transfer device comprises a body comprising a first connecting portion comprising a first fluid channel to fluidically communicate with an interior of a diluent container, a second connecting portion comprising a second fluid channel to fluidically communicate with an interior of a medicament container, a third connecting portion comprising a third fluid channel to fluidically communicate with an interior of a pooling container, and a fourth fluid channel to fluidically communicate with a pump device. A movable part is engaged with and movable relative to the body to transfer the fluid transfer device into one of a first configuration, a second configuration and a third configuration. When in the first configuration, the second fluid channel is fluidically coupled to the third fluid channel, and when in the second configuration, the first fluid channel is fluidically connectable to the third fluid channel.

Fluid transfer device

A medicament delivery device for injecting a medicament is described. The medicament delivery device comprises a housing having a proximal end and a distal end, the housing being configured to receive a medicament container. A plunger is moveable in a longitudinal direction within the housing for dispensing medicament from the medicament container when the medicament container is received within the housing. A plunger drive magnet is operatively coupled to the housing, and the plunger drive magnet is configured to provide a magnetic field. A component is configured to magnetically interact with the magnetic field of the plunger drive magnet so as to cause a force to be exerted on the plunger for causing the plunger to move in the longitudinal direction.

A vial adapter for connecting to an injection vial comprises a barrel and a barrel head with an outlet that is sealed by a pierceable stopper. The vial adapter comprises an adapter body comprising a top wall and a sidewall. The sidewall projects from the top wall in a longitudinal direction to form a receptacle with a distal side of the top wall The receptacle is configured to receive at least a portion of the barrel head. A movable part comprises a base part and an elongated fluid channel extending through the top wall along the longitudinal direction. The elongated fluid channel comprises a proximal channel section merging into a mechanical connector, and a distal channel section with a channel aperture. The movable part is adjustably movable relative to the adapter body along the longitudinal direction to align the channel aperture with an inside surface of the pierceable stopper.

Vial adapter and injection kit for withdrawing a liquid medicament from an injection vial

A vial adapter comprises an adapter body comprising a top wall and a sidewall projecting from the top wall in a longitudinal direction to form a receptacle with a distal side of the top wall. The receptacle is configured to receive at least a portion of a barrel head of an injection vial. A movable part comprises a base part and a spike fixed to the base part. The spike extends through the top wall in a distal direction into the receptacle. An actuating member is mechanically coupled to the movable part, and is movable relative to the adapter body from a start position to an end position along a first direction to induce a distally directed displacement of the movable part relative to the adapter body. The mechanical coupling between the movable part and the actuating member is releasable when the actuating member is in the end position.

A drug delivery device, comprising, an assembly comprising a circlip and a holding element, a device body; a medicament container comprising or adapted to comprise a medicament; wherein the circlip is configured in a deformed state to engage a surface of the medicament container in order to prevent relative movement in at least one direction of the medicament container with respect to the circlip; and wherein the holding element is configured to hold the circlip in the deformed state.

Drug delivery device, assembly for a drug delivery device, method for assembling the drug delivery device and use of the drug delivery device

The present disclosure is directed to adapters for mixing vials of drug products, and more specifically to multi-vial adapters for reconstituting lyophilized drug products and/or diluting concentrated drug products. It is an object to address one or more of drawbacks in connection with the drug preparation process, for example, by simplifying the procedure where multiple vials are required to be diluted or reconstituted in a serial manner. As such, the multi-vial adapters described herein simplify the complexity of preparing and handling multiple vials of drug product, which significantly reduces preparation time, addresses dosing-related challenges like weight-based preparation, reduces drug waste issues, and reduces risks associated sterility and contamination, among other benefits.

Multi-vial adapters for reconstituting or diluting lyophilized or concentrated drug products

A device that regulates, monitors, and provides data on the progress of a large-volume injector during its injection sequence. The device comprises an injector and a monitor assembly. The injector has a syringe having a plunger, and a biasing device that biases the plunger through the syringe. The monitor assembly comprises a resistance unit configured to resist movement of the plunger, a gear connected to the plunger by the resistance unit, and a control unit configured to monitor the position, and regulate the rotation, of the gear. Wherein linear movement of the plunger causes the gear to rotate so that the control unit generates information on the position of the plunger.

Smart injector

A fluid transfer device for transferring a fluid between a diluent container and a medicament container includes a body, a first connecting portion to connect to the diluent container, and a second connecting portion to connect to the medicament container. The first connecting portion includes a first fluid channel to fluidically communicate with an interior of the diluent container, and the second connecting portion comprises a second fluid channel to fluidically communicate with an interior of the medicament container. A third fluid channel is configured to fluidically communicate with the interior of the medicament container and with a pump device. The first fluid channel merges into the second fluid channel to form a first flow path from the diluent container into the medicament container and to form a second flow path from the medicament container into the diluent container.

Growing community of inventors

Weston, MA, United States of America

Haiming Wu