Henan Medinno Pharmaceutical Technology Co., Ltd.

Hai Huang

Liang Lu

Saisai Zhao

Jixuan Zhang

Longzheng Zhang

Junjie Zhu

Xinwei Liao

Shancun Ling

Jiaxin Chen

Xiaolong Wang

The present disclosure relates to a class of JAK inhibitor compounds and uses thereof. Specifically, the present disclosure discloses a compound represented by formula (G), isotopically labeled compound thereof, or optical isomer thereof, geometric isomer thereof, a tautomer thereof or a mixture of various isomers, or a pharmaceutically acceptable salt thereof, or a prodrug thereof, or a metabolite thereof. The present disclosure also relates to the application of the compounds in medicine.

Substituted pyrrolo[3,4-d]imidazoles as JAK inhibitors

The present disclosure relates to substituted pyrrollo[3,4-D]imidazoles as JAK inhibitor compounds and uses thereof. Specifically, the present disclosure discloses a compound represented by formula (I), optical isomer thereof, geometric isomer thereof, a tautomer thereof or a mixture of various isomers, or a pharmaceutically acceptable salt thereof, or a prodrug thereof, or a metabolite thereof. The present disclosure also relates to the application of the compounds in the treatment of JAK-related diseases or disorders. 

Growing community of inventors

Zhengzhou, China

Hai Huang