Korea Advanced Institute of Science and Technology

Inje University Industry-academic Cooperation Foundation

Cheorwon Plasma Research Institute

Innotherapy Inc.

Hae Shin Lee

Moon Sue Lee

Jae Wook Yang

Steven Kim

Sun Ha Paek

Chae Eun Kim

Hye Sook Lee

Mi Young Koh

Seong Woo Ryu

Yoon Jin Lee

Joseph Paul Park

Whui Su Shim

Young Chang Seo

Deuk Yeon Lee

Seon Ki Hong

A composition for preventing or treating dry eye syndrome includes nanocomposite of a polyethylene glycol and a flavonoid as an active ingredient, and in the present invention, a catechin/PEG nanocomposite having increased catechin bioavailability is prepared by using catechins which are an antioxidant and polyethylene glycol which is a hydrophilic polymer used in a drug delivery system, and an increase in tear generation, stabilization of corneal epithelial cells, an increase in conjunctival goblet cells and enhanced anti-inflammatory effects accordance to a PEG dosage by the catechin/PEG nanocomposite are confirmed in a mouse model with dry eye syndrome.

Composition, for preventing or treating dry eye syndrome, containing polyethylene glycol and flavonoid nanocomposite as active ingredient

A method is provided for preparing a catecholamine-based compound by using plasma polymerization, and more specifically, to a method for artificially synthesizing various catecholamines, that is, monomolecular compounds capable of having a hydroxyl group (&#x2014;OH) as an ortho group of a benzene ring and various alkylamines as a para group thereof from a catecholamine precursor material such as phenol or aniline by using dry plasma polymerization.

Method for synthesizing catecholamines by using plasma polymerization

Disclosed is a carbon material for a neurostimulation electrode. The carbon material is composed of a carbon fiber. The carbon fiber has a thickness of 1 to 1000 &#x3bc;m, a linear density of 0.01 to 5.00 g/cm, and an aspect ratio of 100 to 1,000,000. Particularly, the carbon fiber material can be obtained by dry spinning carbon nanotubes, followed by liquid-based densification. The carbon material can be used in the fields of deep brain stimulation, spinal cord stimulation, etc. Also disclosed are an electrode assembly and a neurostimulation device, each including the carbon material.

Bio-implantable electrode assembly

The present invention relates to a method for preparing a double-sided film containing the step of 5 forming a film in the interface between air and the mixture of a polymer comprising amine group (&#x2014;NH) and a compound containing phenol or catechol by exposing the mixture on the air. Particularly, the double-sided film of the present invention is a separation membrane 10 that can separate the interface of liquid phase and gas phase and at the same time can be used as a biomaterial such as a haemostatic and also an waterproof agent. When the film is prepared in a moderate condition by using an enzyme, the film can include proteins and 15 cells, resulting in the multi-functional versatility film that can be useful as a biocatalyst. The versatility film of the present invention, thus, is not expensive and the production method thereof is simple and eco-friendly.

Catecholamine-based versatility film and a preparation method thereof

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Daejeon, South Korea

Hae Shin Lee