Hyperfine Operations, Inc.

Hyperfine Research, Inc.

Icahn School of Medicine at Mount Sinai

Hyperfine, Inc.

Hyperfire Research, Inc.

Hadrien A Dyvorne

Laura Sacolick

Todd Rearick

Cedric Hugon

Jonathan Marc Rothberg

Michael Stephen Poole

Jeremy Christopher Jordan

Rafael O'Halloran

Christopher Thomas McNulty

William Julian Mileski

Alan B Katze, Jr

Carole Lazarus

Michal Sofka

Prantik Kundu

Jo Schlemper

Seyed Sadegh Mohseni Salehi

Ziyi Wang

Jonathan Lowthert

Eddy B Boskamp

Michael Twieg

Khan Mohammad Siddiqui

Priti Balchandani

Seyed Sadegh Moshen Salehi

Seyed Sadegh Mosheni Salehi

Sunli Tang

Tianrui Luo

Techniques are described for controlling components of a Magnetic Resonance Imaging (MRI) system with a single controller, such as a Field Programmable Gate Array (FPGA), by dynamically instructing the controller to issue commands to the components using a processor coupled to the controller. According to some aspects, the controller may issue commands to the components of the MRI system whilst actively receiving commands from the processor to be later issued to the components.

Techniques for dynamic control of a magnetic resonance imaging system

Methods and apparatus for reducing noise in RF signal chain circuitry for a low-field magnetic resonance imaging system are provided. A switching circuit in the RF signal chain circuitry may include at least one field effect transistor (FET) configured to operate as an RF switch at an operating frequency of less than 10 MHz. A decoupling circuit may include tuning circuitry coupled across inputs of an amplifier and active feedback circuitry coupled between an output of the amplifier and an input of the amplifier, wherein the active feedback circuitry includes a feedback capacitor configured to reduce a quality factor of an RF coil coupled to the amplifier.

Radio-frequency coil signal chain for a low-field MRI system

A magnetic resonance imaging (MRI) system and method for acquiring magnetic resonance (MR) images using a pulse sequence implementing driven equilibrium and quadratic phase cycling techniques is provided. The method includes, during a pulse repetition period of a pulse sequence and using a quadratic phase cycling scheme, applying a first RF pulse to deflect a net magnetization vector associated with the subject from a longitudinal plane into a transverse plane; after applying the first RF pulse, applying a first sequence of RF pulses each of which flips the net magnetization vector by approximately 180 degrees within the transverse plane; and after applying the first sequence of RF pulses, applying a second RF pulse to deflect the net magnetization vector from the transverse plane to the longitudinal plane.

Systems and methods for low-field fast spin echo imaging

Techniques for compensating for presence of eddy currents during the operation of a magnetic resonance imaging (MRI) system in accordance with a pulse sequence, the pulse sequence comprising a gradient waveform associated with a target gradient field. The techniques include: compensating for presence of eddy currents during operation of the MRI system at least in part by correcting the gradient waveform using a nonlinear function of a characteristic of the gradient waveform to obtain a corrected gradient waveform; and operating the MRI system in accordance with the corrected gradient waveform to generate the target gradient field.

Eddy current mitigation systems and methods

A magnetic resonance imaging (MRI) system, comprising: a magnetics system comprising: a Bmagnet configured to provide a Bfield for the MRI system; gradient coils configured to provide gradient fields for the MRI system; and at least one RF coil configured to detect magnetic resonance (MR) signals; and a controller configured to: control the magnetics system to acquire MR spatial frequency data using non-Cartesian sampling; and generate an MR image from the acquired MR spatial frequency data using a neural network model comprising one or more neural network blocks including a first neural network block, wherein the first neural network block is configured to perform data consistency processing using a non-uniform Fourier transformation.

Deep learning techniques for magnetic resonance image reconstruction

Techniques of prospectively compensating for motion of a subject being imaged by an MRI system, the MRI system comprising a plurality of magnetics components including at least one gradient coil and at least one radio-frequency (RF) coil, the techniques comprising: obtaining first spatial frequency data and second spatial frequency data by operating the MRI system in accordance with a pulse sequence, wherein the pulse sequence is associated with a sampling path that includes at least two non-contiguous portions each for sampling a central region of k-space; determining a transformation using a first image obtained using the first spatial frequency data and a second image obtained using the second spatial frequency data; correcting the pulse sequence using the determined transformation to obtain a corrected pulse sequence; and obtaining additional spatial frequency data in accordance with the corrected pulse sequence.

Artefact reduction in magnetic resonance imaging

Systems and methods are provided herein for determining whether to extend scanning performed by a magnetic resonance imaging (MRI) system. According to some embodiments, there is provided a method for imaging a subject using an MRI system, comprising: obtaining data for generating at least one magnetic resonance image of the subject by operating the MRI system in accordance with a first pulse sequence; prior to completing the obtaining the data in accordance with the first pulse sequence, determining to collect additional data to augment and/or replace at least some of the obtained data; determining a second pulse sequence to use for obtaining the additional data; and after completing the obtaining the data in accordance with the first pulse sequence, obtaining the additional data by operating the MRI system in accordance with the second pulse sequence.

Systems and methods for dynamically extending magnetic resonance imaging of a subject

A magnetic resonance (MR) imaging system, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, and a sensor configured to detect electromagnetic interference conducted by a patient into an imaging region of the MR imaging system. The sensor may comprise at least one electrical conductor configured for electrically coupling to the patient. The MR imaging system may further comprise a noise reduction system configured to receive the electromagnetic interference from the sensor and to suppress electromagnetic interference in detected MR signals received by the MR imaging system based on the electromagnetic interference detected by the sensor.

System and methods for detecting electromagnetic interference in patients during magnetic resonance imaging

An apparatus for providing a Bmagnetic field for a magnetic resonance imaging system. The apparatus includes at least one permanent Bmagnet to contribute a magnetic field to the Bo magnetic field for the MRI system and a ferromagnetic frame configured to capture and direct at least some of the magnetic field generated by the Bmagnet. The ferromagnetic frame includes a first post having a first end and a second end, a first multi-pronged member coupled to the first end, and a second multi-pronged member coupled to the second end, wherein the first and second multi-pronged members support the at least one permanent Bmagnet.

Ferromagnetic frame for magnetic resonance imaging

An apparatus for controlling at least one gradient coil of a magnetic resonance imaging (MRI) system. The apparatus may include at least one computer hardware processor; and at least one computer-readable storage medium storing processor executable instructions that, when executed by the at least one computer hardware processor, cause the at least one computer hardware processor to perform a method. The method may include receiving information specifying at least one target pulse sequence; determining a corrected pulse sequence to control the at least one gradient coil based on the at least one target pulse sequence and a hysteresis model of induced magnetization in the MRI system caused by operation of the at least one gradient coil; and controlling, using the corrected gradient pulse sequence, the at least one gradient coil to generate one or more gradient pulses for imaging a patient.

Correcting for hysteresis in magnetic resonance imaging

Techniques are provided for imaging a subject. A magnetic resonance imaging (MRI) system may use at least one RF coil to generate an initial MR data set for an initial image of the subject. The MRI system may use the initial MR image to determine a difference in orientation between a current orientation of the subject in the initial MR image and a target orientation of the subject. The MRI system may use the determined difference in orientation to determine an adjustment to a gradient pulse sequence for controlling at least one gradient coil. The MRI system may apply the determined adjustment to the gradient pulse sequence to obtain an adjusted gradient pulse sequence. The MRI system may generate an adjusted MR data set using the adjusted gradient pulse sequence, and a second MR image of the subject using the adjusted MR data set.

Systems and methods for performing magnetic resonance imaging with reduced operator interaction

According to some aspects, a portable magnetic resonance imaging system is provided, comprising a Bmagnet configured to produce a Bmagnetic field for an imaging region of the magnetic resonance imaging system, a noise reduction system configured to detect and suppress at least some electromagnetic noise in an operating environment of the portable magnetic resonance imaging system, and electromagnetic shielding provided to attenuate at least some of the electromagnetic noise in the operating environment of the portable magnetic resonance imaging system, the electromagnetic shielding arranged to shield a fraction of the imaging region of the portable magnetic resonance imaging system. According to some aspects, the electromagnetic shield comprises at least one electromagnetic shield structure adjustably coupled to the housing to provide electromagnetic shielding for the imaging region in an amount that can be varied. According to some aspects, substantially no shielding of the imaging region of the portable magnetic resonance imaging system is provided.

Electromagnetic shielding for magnetic resonance imaging methods and apparatus

Techniques for removing artefacts, such as RF interference and/or noise, from magnetic resonance data. The techniques include: obtaining input magnetic resonance (MR) data using at least one radio-frequency (RF) coil of a magnetic resonance imaging (MRI) system; and generating an MR image from input MR data at least in part by using a neural network model to suppress at least one artefact in the input MR data.

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Branford, CT, United States of America

Hadrien A Dyvorne