Research, Incorporated

H William Prusoff

David C Ward

Tai-Shun Lin

Yung-Chi Cheng

John P Neenan

The compound 5-iodo-5'-amino-2',5'-dideoxycytidine and the pharmaceutically acceptable acid addition salts thereof are potent inhibitors of herpes simplex virus.

5-Iodo-5'-amino-2',5'-dideoxycytidine and the pharmaceutically

The known compound 5'-amino-5'-deoxythymidine and the pharmaceutically acceptable acid addition salts thereof are potent inhibitors of herpes simplex virus and compositions containing one or more of them are therapeutically useful.

Compositions containing 5-amino-5-deoxythymidine and pharmaceutically

The compounds 5'-amino-2',5'-dideoxy-5-iodouridine; 5'-amino-2',5'-dideoxy-5-bromouridine; and the pharmaceutically acceptable acid addition salts thereof have been found to be potent inhibitors of herpes simplex virus.

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H William Prusoff