University of Colorado

University of California

Leland Stanford Junior University

Rensselaer Polytechnic Institute

H Peter Chase

Francis J Doyle, Iii

Bruce A Buckingham

Fraser Cameron

Darrell M Wilson

B Wayne Bequette

Matthew Stenerson

This invention provides ambulatory medical systems that include a monitoring device, a therapeutic substance administering device, and a receiver-controller for receiving a signal generated by the monitoring device and controlling the therapeutic substance administering device based on the information received from the monitoring device. The invention also provides methods for using the same.

Medical systems and methods of use

Techniques for controlling an insulin pump include determining values for parameters selected from a group including a first prediction time horizon, a predicted glucose threshold (Goff) for turning the insulin pump off, a maximum shut off time within a time window, and duration of the time window. A safety rule is determined based on the maximum shut off time within the duration. Glucose readings are collected up to a current time. An expected current glucose value G and glucose temporal rate of change are determined based only on the glucose readings and a Kalman filter configured for noisy glucose readings. A glucose level (Gh1) is predicted for a future time that is the prediction time horizon after the current time. A command is issued to shut off the insulin pump if it is determined both that Gh1 is less than Goff and that the safety rule is satisfied.

Kalman filter based on-off switch for insulin pump

Growing community of inventors

Denver, CO, United States of America

H Peter Chase