Albion International, Inc.

Albion Laboratories, Inc.

Other

The Procter Gamble Company

Brigham Young University

Metagenics, Inc.

Infinity, Inc.

H Dewayne Ashmead

Harvey H Ashmead

Mark Pedersen

Stephen D Ashmead

Clayton Ericson

Robert B Jeppsen

Stephen M Paul

Kenneth Thomas Smith

David C Wheelwright

Earl C Christiansen

Janeel Henderson

R Charles Thompson

Kris Eugene Spence

Stanley A Bynum

Douglas D Grant

Robert V Petersen

Max R Motyka

Darrell J Graff

Rick Harnish

Metal carnitine chelates comprising carnitine chelated to a nutritionally relevant metal can be used for general nutrition as well as well as to treat a variety of health related problems and symptoms. For example, metal carnitine chelates can be used to maintain good cardiovascular health, increase male fertility, enhance weight loss, provide mineral and/or carnitine supplements for mineral- and/or carnitine-deficient subjects, and reduce alcohol dependency and associated symptoms. Nutritionally relevant metals that can be used include copper, zinc, magnesium, calcium, iron, chromium, and manganese, to name a few.

Metal carnitine chelates

Hypoallergenic metal amino acid chelate compositions, hypoallergenic formulations containing hypoallergenic metal amino acid chelates, methods of preparing hypoallergenic metal amino acid chelate, and methods of administering hypoallergenic metal amino acid chelates are provided. Specifically, the present invention provides metal amino acid chelates that are substantially free of allergens such that administration of the metal amino acid chelates to a subject in an effective amount to cause a medicinal or nutritional result does not produce a discernable adverse allergic reaction. The metal amino acid chelates can include chelates having a naturally occurring amino acid to metal molar ratio of from about 1:1 to 4:1.

Hypoallergenic metal amino acid chelates and metal amino acid chelate-containing compositions

The present invention is drawn to an ephedra- and artificial stimulant-free energy promoting composition, comprising effective amounts of a magnesium amino acid chelate, a B vitamin, a pyruvate salt, and rhodiola. These ingredients work synergistically together to provide energy, without the use of artificial stimulants, caffeine, or ephedrine. Additional amino acid chelates can also be present, such as iron amino acid chelate, zinc amino acid chelate, copper amino acid chelate, manganese amino acid chelate, chromium amino acid chelate, and mixtures of second amino acid chelates.

Energy generating composition

Described are cereal grain kernels fortified with iron and calcium. Also described is a process for making cereal grain kernels fortified with iron and calcium, the process comprising providing cereal grain kernels and mixing said kernels with a composition comprising an iron source and a calcium source.

Cereal grain kernels fortified with iron and calcium

A method of enhancing the solubility of iron amino acid chelates and iron proteinates is disclosed. This is accomplished by mixing an effective amount of an organic acid solubilizing agent into existing iron amino acid chelates or iron proteinates. The iron amino acid chelates and iron proteinates may have a ligand to metal molar ratio from about 1:1 to 4:1, preferably 2:1 to 3:1.

Enhancing solubility of iron amino acid chelates and iron proteinates

A composition and method of preparing amino acid chelates and complexes free of interfering ions by blending an amino acid ligand, a calcium oxide and/or hydroxide, and a hydrated metal sulfate salt, placing the blend in a closed environment, heating the blend, and allowing the blend to react is disclosed and described. By heating at low to moderate temperatures in an enclosed environment, the waters of hydration of the metal salt are retained in the enclosed environment and serve to provide the moisture necessary to enable a bonding reaction to take place between the electron rich functional groups of the ligand and the metal ion of the hydrated metal sulfate salt. Additionally, calcium sulfate is formed which can be maintained in the final product.

Composition and method for preparing amino acid chelates and complexes free of interfering complex ions

Compositions and methods of preparing amino acid chelates and complexes are disclosed and described. Specifically, by (a) combining a hydrated metal sulfate salt with an amino acid ligand to form a particulate blend, (b) placing the particulate blend in an enclosed environment; and (c) applying heat to the particulate blend in the enclosed environment causing the waters of hydration of the metal sulfate salt to be released into the enclosed environment causing a reaction resulting in the formation of an amino acid chelate or complex by effecting the reaction between functional electron rich groups of the amino acid ligand and a metal ion of the metal sulfate salt. The waters of hydration serve to provide the water necessary to enable a bonding reaction to take place between the electron rich functional groups of the amino acid ligand and the metal ion of the hydrated metal sulfate salt.

Composition and method for preparing amino acid chelates and complexes

A non-steroid containing anabolic nutrient formulation for the building and sustaining of muscle mass in humans or other warm-blooded animals, that enables the body to synthesize and maintain muscle at a mass and in a manner optimally suited to the genetic makeup of that person or animal. The formulation comprises effective amounts of a chromium salt, complex or chelate and a magnesium glycyl glutaminate chelate. Optionally, one or more additional nutrients selected from the group consisting of a magnesium amino acid chelate or proteinate, an .alpha.-glutaric acid salt of ornithine, creatine or a salt thereof, and a branched chain amino acid selected from the group consisting of leucine, isoleucine and valine and mixtures thereof may be included.

Non-steroidal anabolic composition

A method for facilitating digestion of carbohydrates into simple sugars in warm-blooded animals by maintaining and enhancing the natural disaccharidase enzymatic activity in the mucosal cells of the small intestines. Iron is an essential mineral and other minerals selected from the group consisting of copper, zinc, manganese and cobalt are provided in the form of amino acid chelates having a ligand to mineral molar ratio of at least 1:1, a molecular weight of no more than 1500 daltons and a stability constant of between about 10.sup.6 and 10.sup.16 and administered orally. Additionally, magnesium and chromium, as amino acid chelates, may be added to improve disaccharidase activity as may potassium in inorganic salt form or as a 1:1 ligand to potassium amino acid complex. The minerals are taken into the mucosal cells lining the small intestine where they are utilized to facilitate the production and activity of disaccharidase enzymes such as maltases, sucrase and lactase. These enzymes promote the hydrolysis of disaccharides resulting from degradation of more complex carbohydrates or of sucrose and lactose into simple sugars or monosaccharides for absorption from the intestinal tract.

Food energy utilization from carbohydrates in animals

A method for alleviating stress and/or stress related symptoms in humans and other warm-blooded animals particularly when such symptoms are complicated by intestinal malabsorption of minerals is disclosed. Chromium and, optionally, one or more other minerals selected from the group consisting of copper, zinc, manganese, iron and selenium are provided in the form of amino acid chelates having a ligand to mineral ratio of at least 1:1, a molecular weight of no more than 1500 and a stability constant of between about 10.sup.6 and 10.sup.16 and administered orally. They are absorbed from a portion of the intestinal tract other than that utilized for the absorption of cations. The method is particularly adapted to reducing and/or controlling levels of serum cortisol in humans or other animals. The presence of symptoms of stress may first be confirmed or the compositions may be administered as a prophylactic.

Composition and method for alleviating stress in warm-blooded animals

A palatable metal amino acid chelate for administration to humans and other warm-blooded animals is disclosed wherein there are sufficient ligands to provide ionic and coordinate covalent bonds equal to the coordination number of the central metal ion while, at the same time, maintaining charge balance in the chelate molecule. There must be at least one ligand of the polydentate type which must be an .alpha.-amino acid with the further proviso that any unidentate or polydentate ligand(s) must be charge balanced organic ligands. Charge balancing may be accomplished by means of an organic acid and dicarboxylic, hydroxycarboxylic, hydroxydicarboxylic or hydroxytricarboxylic acids in particular, which maintains the chelate molecule as an optimum pH for purposes of stability and palatability.

Amino acid chelates having improved palatability

A composition which provides for sustained energy and nutrition to support an anabolic physiological state in humans comprises a blend of simple sugars and more complex carbohydrates, partially hydrolyzed protein, and, at least, magnesium in the form of an amino acid chelate. Preferably the carbohydrate source is a blend of about 5-45% crystalline fructose and 55-95% glucose polymers by weight. Other ingredients, including lipids, bioavailable minerals in the form of amino acid chelates, anabolic nutrients, vitamins, antioxidants, and lipotropic agents may be added as desired to provide an optimal sustained energy and anabolic nutrition formulation. When administered, the carbohydrate blend, protein source, and amino acid chelates facilitate sustained energy and delivery of nutrients to appropriate sites within the body for efficient utilization in anabolic physiology.

Improved sustained energy and anabolic composition and method of making

A method for maintaining the immune system of a warm-blooded animal afflicted with a form of antigenic morbidity exacerbated by intestinal malabsorption of minerals is disclosed. Minerals selected from the group consisting of copper, zinc, manganese, iron and selenium are provided in the form of amino acid chelates having a ligand to mineral ratio of at least 1:1, a molecular weight of no more than 1500 and a stability constant of between about 10.sup.6 and 10.sup.16 and administered orally. They are absorbed from a portion of the intestinal tract other than that utilized for the absorption of cations. The method is particularly adapted to the maintaining of the immune system of a warm-blooded animal infected by a virus which compromises the absorption of trace minerals via the normal cationic absorption route. The presence of intestinal malabsorption in the host showing symptoms of antigenic morbidity is first confirmed. Based on previous data of mineral levels and ratios in assayed tissues and/or body fluids of similarly infected hosts compared with mineral levels and ratios in healthy hosts, an amino acid chelate composition is formulated and administered to the afflicted animal(s) for such time as is necessary for the immune system to be properly maintained.

Composition and method for enhancing the immune system in warm-blooded

Amino acid chelates having a ligand to divalent metal mole ratio of at least 2:1 and having a molecular weight of not more than 1500 and preferably not more than 1000 and also having a stability constant of between about 10 and 10 are formulated for delivery to one or more specific tissue sites within a mammal. The ligand utilized in formulating the amino acid chelate is a naturally occuring amino acid or a dipeptide, tripeptide or quadrapeptide thereof. The selection of an appropriate ligand with which to form the chelate provides a product that, when entering the bloodstream of the mammal, either by mean of oral ingestion or injection, has a propensity to migrate to one or more targeted tissue sites within the mammal.

Amino acid chelated compositions for delivery to specific biological

Flavored, effervescent, water soluble compositions containing water-soluble and oil-soluble vitamins and amino acid chelated minerals in bioavailable form are contained in a composition consisting of 20-30% of a vitamin blend consisting of water-soluble and oil-soluble vitamins adsorbed on a lactose carrier containing a minor amount of propylene glycol, 5-25% of one or more amino acid chelated minerals selected from the group consisting of calcium, magnesium, iron, zinc, copper and manganese, 20-45% citric acid, 5-25% of one or more alkali or alkaline earth metal bicarbonates or carbonates, 1-5% flavoring agent, 0.5-2% of a sweetening agent and sufficient additional lactose carrier to provide the desired vitamin and mineral content per unit dosage which will normally vary between about 2 and 6 grams. When dissolved in water a flavored, lightly carbonated drink is provided which will contain in soluble bioavailable form between about 50 to 100% of the U.S. RDA of one or more vitamins contained in a dosage unit of the composition and between about 20 to 50% of the U.S. RDA of one or more of the trace minerals iron, zinc, copper and magnesium as contained in a unit dosage of the composition as amino acid chelates. Separate effervescent vitamin compositions without minerals and mineral compositions without vitamins are also disclosed.

Growing community of inventors

Fruit Heights, UT, United States of America

H Dewayne Ashmead