Trigen Gmbh

Helmholtz Zentrum Munchen Deutsches Forschungszentrum Fur Gesundheit Und Umwelt

Corimmun Gmbh

Götz Münch

Andreas Bültmann

Meinrad Gawaz

Martin Ungerer

Steffen Massberg

Mario Peluso

Elisabeth Kremmer

The present invention provides anti-thrombotic agents, methods for screening for said anti-thrombotics agents and methods of treating thrombotic and other cardiovascular disorders.

Antibodies which bind to epitopes of glycoprotein VI

The present invention provides a fusion protein comprising (1) the extracellular domain of glycoprotein VI or a variant thereof that is functional for binding to collagen and (b) the Fc domain of the immunoglobulin or a function-conservative part thereof, characterized by a polypeptide chain having an amino acid sequence as shown in FIG.and whereby the fusion protein is obtainable by a process which provides the fusion protein in the form of a specific dimer.

Immunoadhesin comprising a glycoprotein VI domain

The present invention provides a fusion protein comprising (a) the extracellular domain of glycoprotein VI or a variant thereof that is functional for binding to collagen and (b) the Fc domain of an immunoglobulin or a function-conservative part thereof, characterised by a polypeptide chain having an amino acid sequence as shown in FIG.and whereby the fusion protein is obtainable by a process which provides the fusion protein in the form of a specific dimer.

Polynucleotides encoding immunoadhesins comprising a glycoprotein VI domain

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Munich, Germany

Götz Münch