Glycom A/s

Carbocode S.a.

Societe Des Produits Nestle S.a.

Glycom Aps

Nestec S.a.

Gyula Dekany

Elise Champion

Markus Hederos

Lars Kröger

Christoph Röhrig

Andreas Schroven

István Bajza

Ioannis Vrasidas

Károly Ágoston

Pauline Peltier-Pain

Bruce McConnell

Markus Jondelius Hederos

Pierre Chassagne

Martin Matwiejuk

Piroska Kovács-Pénzes

Julien Boutet

Christian Risinger

Ferenc Horváth

Marie Bøjstrup

Ágnes Ágoston

Eric Samain

Katrine Bych

Györgyi Osztrovszky

Ted Johanson

Sándor Demkó

Gergely Pipa

Andreas Vogel

Peter Erdmann

Péter Trinka

Manos Papadakis

Margit Pedersen

Peter Becker

Andrea Schwarz

Dóra Molnár-Gábor

László Kalmár

Ignacio Figueroa Pérez

Andras Nagy

Jorge Santos

Norbert Sprenger

Nikolay Khanzhin

Dominique Brassart

Sebastian Bartsch

Benjámin Podányi

Ramona Schmiedel

Ignacio Pérez Figueroa

Karoly Agoston

Ignacio Fegueroa Pérez

Erzsébet Czinege

Paulo Vital

Ignacio Figuero-Pérez

Ignacio Figueroa-Pérez

Gábor Kádár

Sándor Demkò

Krisztián Kovàcs

Ferenc Horvàth

Ágnes Jànosi

Irme Kovács

Ågnes Jánosi

Dóra Molnàr-Gàbor

Nicolas Fierfort

Christophe Pain

Imre Kovács

The invention relates to a method for selective crystallization of 2'-fucosyllactose (2′-FL) from an aqueous solution comprising 2′-FL and one or more other fucosylated carbohydrates by adding acetic acid to the solution. The aqueous solution is separated from an aqueous culture medium prior to crystallization.

Separation of 2'-FL from a fermentation broth

The present invention relates to sphingolipids, a method for the production of sphingoid bases, especially sphingosine, and novel derivatives thereof. The sphingoid bases are herein produced by making use of a vinylogous amide-type protecting group. The resulting vinylogous amide compounds enable an easy and effective production of sphingoid bases, especially sphingosine.

Sphingosine/sphingoid base production

The invention relates to a genetically modified microorganism for making a oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source.

Oligosaccharide production

The present invention relates to several novel 1-O-glycosylated sphingoid bases and to a production method thereof, as well as to uses of the 1-O-glycosylated sphingoid bases. Sphingoid bases carrying a vinylogous amide-type protecting group are used herein for the production of 1-O-glycosylated sphingoid bases. These vinylogous amide compounds enable an easy and effective production of 1-O-glycosylated sphingoid bases.

Glycosylated sphingoid bases and production thereof

A mixture of human milk oligosaccharides that consists essentially of 3'-O-sialyllactose, a component A which is either 3-O-fucosyllactose or lacto-N-tetraose, a component B which is 3-0-fucosyl-3&#x2032;-O-sialyllactose when component A is 3-O-fucosyllactose and sialyllacto-N-tetraose a, when component A is lacto-N-tetraose and optionally lactose as a fourth component. The mixtures are made by treating 3&#x2032;-O-sialyllactose and component A with an &#x3b1;2,3-transsialidase. The mixtures are for use in anti-bacterial and anti-viral compositions, and for promoting the development ofand

Mixtures of human milk oligosaccharides comprising 3'-O-sialyllactose

The invention relates to a mixture of human milk oligosaccharides that consists essentially of:

Mixtures of HMOs

The invention relates to a genetically modified microorganism for making a recombinant oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source. The one or more genes encoding a sucrose utilization system are preferably one or more genes encoding a heterologous PTS-dependent sucrose utilization transport system, such as the scr genes.

A mixture of human milk oligosaccharides that consists essentially of 6'-SL, LNnT and LSTc, made by treating 6&#x2032;-SL and LNnT in the presence of an &#x3b1;2,6-transsialidase.

Ternary mixtures of 6'-SL, LNnT and LST c

The invention relates to a method for selective crystallization of 2'-FL from an aqueous solution comprising 2&#x2032;-FL and one or more other fucosylated carbohydrates by adding acetic acid to the solution.

A mixture of human milk oligosaccharides that consists essentially of 3'-O-sialyllactose, a component A which is either 3-O-fucosyllactose or lacto-N-tetraose, a component B which is 3-O-fucosyl-3&#x2032;-O-sialyllactose when component A is 3-O-fucosyllactose and sialyllacto-N-tetraose a, when component A is lacto-N-tetraose and optionally lactose as a fourth component. The mixtures are made by treating 3&#x2032;-O-sialyllactose and component A with an &#x3b1;2,3-transsialidase. The mixtures are for use in anti-bacterial and anti-viral compositions, and for promoting the development ofand

Mixtures of human milk oligosaccharides comprising 3 '-O-sialyllactose

Crystalline difucosyllactose, useful in a pharmaceutical composition and a nutritional composition, is disclosed.

Crystalline difucosyllactose

A method for the manufacture an infant formula or an infant nutritional product comprising mixture of human milk oligosaccharides is disclosed. The method involves the catalytic hydrogenolysis of compounds of the general formula 1 and 2 with particular oligosaccharide profiles.

Nutritional products comprising human milk oligosaccharides and methods for manufacture thereof

The invention provides engineered enzymes of transsialidase and/or sialyl transferase activity that have increased regioselectivity and/or increased thermostability.

Mutated sialidases

Mutated fucosidases are provided demonstrating improved properties in terms of thermal stability and transfucosidase synthetic performance compared with a wild type transfucosidase isolated fromsubsp.

Mutated fucosidase

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Sinnamon Park, Australia

Gyula Dekany