Richter Gedeon Vegyeszeti Gyar Rt

Gyozo Hortobagyi

Eva Palosi

Egon Karpati

Gyorgy Hajos

Elemer Ezer

Lilla Forgach

Eszter Cholnoky

Katalin Gidai

Laszlo Szporny

Laszio Szporny

Erzsebet Takacs

Ilona Kolbe

Marianne Skvorecz Nee Hajnoczy

Janos Dobo

Katalin Hoffmann Nee Vas

A coating ensuring the controlled release of a biological active ingredient, which can be incorporated in the coating or is surrounded thereby, consists of a varnish-forming polymer selected from the group which consists of cellulose triacetate containing polyethylene glycol as an emollient and vinyl chloride-vinyl acetate copolymer with glycerol as an emollient, and an aqueous phase dispersed in the polymer and consisting of particles of a diameter up to 20 microns, the aqueous phase making up 2% to 30% of the volume of the coating. The active ingredient is preferably a pharmaceutical agent affecting the circulatory system or a psychotropic agent.

Coating ensuring a controlled release of active ingredients of

Ulcer production in animals is prevented during prolonged antiphlogistic treatment with ulcerogenic quantities of indomethacin by using it in a composition of 1 part of indomethacin to 7.5 to 25 parts, preferably 10 parts by weight of a salicylate. Indomethacin is the most potent ulcerating compound among approved non-steroid antiinflammatory agents.

Treating mammalian subject sensitive to indomethacin ulcerogenisis

Ulcer production in animals is prevented during prolonged antiphlogistic treatment with ulcerogenic quantities of phenylbutazone by using it in a composition of 1 part of antiphlogistic to 0.2 to 50 parts by weight of alkali metal salicylate.

Antiphlogistic composition of phenylbutozone and alkali salicylate and

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Budapest, Hungary

Gyozo Hortobagyi