Other

Smithkline Beecham Corporation

Glaxo Group Limited

Smithkline Beecham Laboratoires Pharmaceutiques

Nikem Research S.r.l.

Guy Marguerite Marie Gerard Nadler

Carlo Farina

Neil David Pearson

Stefania Gagliardi

Catherine Genevieve Yvette Dartois

Roger Edward Markwell

Jeffrey Michael Axten

Luca Francesco Raveglia

Giuseppe Giardina

Mario Grugni

Michel Jean Roger Martin

Pietro A T Novella

Quinoline and naphthridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans.

Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents

Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.

Bicyclic nitrogen-containing heterocyclic derivatives for use as antibacterials

A compound of formula (I):or a salt thereof, or a solvate thereof, wherein Ra represents a group Rwhich is hydrogen, alkyl or optionally substituted aryl and Rb represents a moiety of formula (a):wherein X represents a hydroxy or an alkoxy group wherein the alkyl group may be substitued or unsubstituted or X represents a group NRRwherein Rand Reach independently represent hydrogen, alkyl, substituted alkyl, optionally substituted alkenyl, optionally substituted aryl, optionally substituted arylalkyl, an optionally substituted heterocyclic group or an optionally substituted heterocyclylalkyl group, or Rand Rtogether with the nitrogen to which they are attached form a heterocyclic group; Rrepresents an alkyl or a substituted or unsubstituted aryl group; and R, Rand Reach independently represent hydrogen, alkyl, aryl or substituted aryl; Rand Reach independently represent hydrogen, hydroxy, amino, alkoxy, optionally substituted aryloxy, optionally substituted benzyloxy, alkylamino, dialkylamino, halo, trifluoromethyl, trifluoromethoxy, nitro, alkyl, carboxy, carbalkoxy, carbamoyl, alkylcarbamoyl, or Rand Rtogether represent methylenedioxy, carbonyldioxy or carbonyldiamino; and Rrepresents hydrogen, hydroxy, alkynoyl, alkyl, aminoalkyl, hydroxyalkyl, carboxyalky, carbalkoxyalkyl, carbamoyl or aminosulphonyl; a process for preparing such a compound, a pharmaceutical composition containing such a compound and the use of such a compound in medicine.

Indole derivatives for the treatment of osteoporosis

Quinoline derivatives as NK-2 and NK-3 receptor ligands

A compound of formula (I): or a salt thereof, or a solvate thereof, wherein Ar represents substituted or unsubstituted aryl, wherein the optional substituents are selected from alkyl, hydroxy or alkoxy or, if attached to adjacent carbon atoms any two substituents together with the carbon atoms to which they are attached may form a fused heterocyclic ring of five to six atoms wherein one, two or three of the said atoms are oxygen or nitrogen; A represents a C n-alkylene group wherein each carbon is optionally substituted by 1 or 2 C alkyl groups; R represents hydrogen, alkyl, alkenyl or cycloalkyl; one or two of of the group of R , R and R represents nitro the remaining members of the group of R , R and R represent hydrogen; X represents a &mdash;CO&mdash;NH&mdash; moiety; and Z represents C n-alkylene group wherein each carbon is optionally substituted 1 or 2 C alkyl groups; a process for preparing such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.

Nitro-benzamides useful as anti-arrhythmic agents

Indole derivatives useful A.O. for the treatment of osteoporosis

Growing community of inventors

Rennes, France

Guy Marguerite Marie Gerard Nadler