University of Florida Research Foundation Inc

Usbiomaterials Corporation

Other

Guy LaTorre

Christopher D Batich

Larry L Hench

Jon Kenneth West

June Wilson

William Toreki

James S Marotta

David C Greenspan

William Toreki, Iii

Alice D Greenspan

Compositions and methods for treating nails and adjacent tissues are disclosed. The compositions include non-interlinked particles of bioactive glass, alone or in combination with therapeutic agents, hydrophilic polymers, and other optional components. The compositions optionally include an appropriate aqueous carrier for topical administration. The methods involve applying an effective nail-enhancing amount of the composition to the nails and adjacent tissues for a sufficient amount of time to cause the formation of a hydroxyapatite or other calcium phosphate mineral layer on the nail surface.

Compositions and methods for treating nails and adjacent tissues

Percutaneous implants are disclosed including a portion implantable into a patient, a dermal bonding region capable of forming a bond between the implant and a dermal layer of the patient after the implantable portion is implanted into the patient, and the dermal bonding region including a substrate with a discontinuous coating of particulate bioactive glass wherein the average spacing between the particles of bioactive glass is predetermined and at least about 20 microns prior to implantation into the patient. Also disclosed are bioactive coatings including a substrate and fibers and/or particles of bioactive glass distributed on the substrate with a predetermined average interfiber distance of at least about 20 microns.

Percutaneous biofixed medical implants

The present invention relates to injectable suspensions of bio-active glass and dextran or a dextran derivative for the repair of soft tissue or hard bone in mammals, especially humans. In one embodiment, the dextran derivatives include free radical polymerizable groups, which can be polymerized following injection into a patient.

Injectable bio-active glass in a dextran suspension

A moldable bioactive composition including (a) bioactive particles of bioactive glass, glass-ceramics, calcium phosphates, calcium apatites, or mixtures thereof; and (b) a biodegradable polysaccharide carrier including a polysaccharide with an average molecular weight of about 200,000-5,000,000.

Moldable bioactive compositions

The present invention relates to novel injectable aqueous suspensions of bio-active glass and dextrans for the repair of soft tissue or hard bone of mammals, especially in humans.

Growing community of inventors

Gainesville, FL, United States of America

Guy LaTorre