Societe De Conseils De Recherches Et D'applications Scientifiques (s.c.r.a.s.)

Guy Lallement

Jean-Marc Kamenka

Pierre Bernard D'Arbigny

A method of inhibiting effects of exogenous neurotoxic or neurotoxinic products in warm-blooded animals comprising administering to warm-blooded animals before exposure to said products an inhibitorily effective amount of reversible cholinesterase inhibitor selected from the group consisting of pyridostigmine and physostigmine followed by administration of an inhibitorily effective amount of 2-methyl-1-(1-piperidinyl)-1-(2-thienyl)-cyclohexane in substantially pure racemic, diastereoisomeric or enantiomeric form.

Therapeutic use of a thienylcyclohexylamine derivative

A method of inhibiting effects of neurotoxic products in warm-blooded animals comprising administering to warm-blooded animals an amount of 2-methyl-1-(1-piperidinyl)-1-(2-thienyl)-cyclohexane in substantially pure racemic, diastereoisomeric or enantiomeric form effect to inhibit effects of neurotropic products and mixtures of thienyl cyclohexylamine and at least one member of the group consisting of anticholinergic, anticonvulsant or cholinesterase-reactivating substances.

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Seyssins, France

Guy Lallement