Alcon Lensx, Inc.

Vialase, Inc.

Amo Development, LLC

Alcon, Inc.

Intralase Corporation

Novartis Ag

Guy Holland

Ferenc Raksi

Tibor Juhasz

Ilya Goldshleger

Carlos German Suarez

Manu Sharma

Eric R Mikula

Wesley W Lummis

Hadi Srass

Ronald Michael Kurtz

Ruben Zadoyan

Adam Juhasz

Kostadin Vardin

Marcel Bouvier

Zsolt Bor

Muhammad Al-Qaisi

Virginia Lin

Joselito T Tambo

Attila Raksi

Scott A Delong

Ronald M Kurtz

Christopher Horvath

Jesse D Buck

Michael F Brownell

Keith Watanabe

Valentina Doushkina

Zolt Bor

Muhammad K Al-Qaisi

Llya Goldshlege

A target volume of ocular tissue is treated with a laser having a direction of propagation toward the target volume, where the target volume is characterized by a distal extent, a proximal extent, and a lateral extent. A layer of tissue at an initial depth corresponding to the distal extent of the target volume is initially photodisrupted using a femtosecond laser by scanning the laser in multiple directions defining an initial treatment plane. Tissue at one or more subsequent depths between the distal extent of the target volume and the proximal extent of the target volume is subsequently photodisrupted using a femtosecond laser by moving a focus of the laser in a direction opposite the direction of propagation of the laser and then scanning the laser in multiple directions defining a subsequent treatment plane. Photodisruption is repeated at different subsequent depths until tissue at the proximal extent of the target volume is photodisrupted.

Surgical system procedure for treatment of the trabecular meshwork and Schlemm's canal using a femtosecond laser

A target volume of ocular tissue of an irido-corneal angle of an eye is treated by moving a focus of a laser through the target volume of ocular tissue, and photodisrupting the target volume of ocular tissue at a plurality of spots as the focus is moved through the target volume of ocular tissue. The focus is moved by transverse scanning the focus between at least one of: a first circumferential boundary and a second circumferential boundary of the target volume of ocular tissue, and a first azimuthal boundary and a second azimuthal boundary of the target volume of ocular tissue, and axial scanning the focus between a distal extent and a proximal extent of the target volume of ocular tissue.

System and method for clearing an obstruction from the path of a surgical laser

A target surface in an eye is located using a dual aiming beam apparatus that transmits a first aiming beam of light and a second aiming beam of light. An optics subsystem receives a laser beam from a laser source, the first aiming beam of light, and the second aiming beam of light, and directs the beams of light to be incident with the target surface and aligns the beams of light such that they intersect at a point corresponding to a focus of the laser beam. An imaging apparatus captures an image of the target surface including a first spot corresponding to the first aiming beam of light and a second spot corresponding to a second aiming beam of light. A separation between the spots indicates that the focus is away from the target surface, while overlapping spots indicate the focus is at or on the target surface.

System and method for locating a surface of ocular tissue for glaucoma surgery based on dual aiming beams

A look-up table for use in determining an energy parameter for photodisrupting ocular tissue with a laser is generated by determining a plurality of individual spot size distributions, wherein each of the plurality of individual spot size distributions is based on a different set of simulated data and includes an expected spot size of a laser focus at each of a plurality of locations within a modeled target volume of ocular tissue. The plurality of individual spot size distributions are combined to obtain a final spot size distribution that includes a final expected spot size of the laser focus at the plurality of locations of the focus within the modeled target volume of ocular tissue. An energy value is assigned to the plurality of locations of the focus within the modeled target volume of ocular tissue based on the final expected spot size at that location.

System and method for laser treatment of ocular tissue based on patient biometric data and apparatus and method for determining laser energy based on an anatomical model

A method of imaging and treating ocular tissue of an eye having a cornea, an iris, an anterior chamber, an irido-corneal angle, and a direction of view includes establishing a common optical path through the cornea and the anterior chamber into the irido-corneal angle for each of an optical coherence tomography (OCT) beam and a laser beam, where the common optical path is offset from an optical axis within the direction of view. The method also includes obtaining a circumferential OCT image of the irido-corneal angle, obtaining an azimuthal OCT image of the irido-corneal angle, and determining a treatment pattern for a volume of ocular tissue of the irido-corneal angle based on the circumferential OCT image and the azimuthal OCT image. The method further includes delivering optical energy through the laser beam in accordance with the treatment pattern.

Method, system, and apparatus for imaging and surgical scanning of the irido-corneal angle for laser surgery of glaucoma

A device for visualizing an irido-corneal angle of an eye through a window of a patient interface configured to be placed on the eye includes and optics structure and at least one imaging apparatus. The optics structure is configured to engage with the patient interface to provide a line of sight through the window in the direction of the irido-corneal angle, and to subsequently disengage from the patient interface. The imaging apparatus is associated with the optics structure and aligned with the line of sight to enable capturing an image of the eye including the irido-corneal angle.

Alignment and diagnostic device and methods for imaging and surgery at the irido-corneal angle of the eye

An OCT imaging system may include an OCT light source operable to emit an OCT light beam, and a beam splitter operable to split the OCT light beam into a sample beam, transferred to a sample arm waveguide, and a reference beam, transferred to a reference arm waveguide. The sample arm waveguide and the reference arm waveguide may be coupled together within a cladding, wherein the cladding improves a calibration of a generated OCT image by fixing axial movement of the sample arm and reference arm waveguides relative to one another. By routing long reference and sample arm waveguide fibers together in the OCT system using a sheath/cladding, OCT image offset due to asymmetrical fiber stretching can be minimized or eliminated.

Common path waveguides for stable optical coherence tomography imaging

A target volume of ocular tissue is treated with a laser having a direction of propagation toward the target volume, where the target volume is characterized by a distal extent, a proximal extent, and a lateral extent. A layer of tissue at an initial depth corresponding to the distal extent of the target volume is initially photodisrupted using a femtosecond laser by scanning the laser in multiple directions defining an initial treatment plane. Tissue at one or more subsequent depths between the distal extent of the target volume and the proximal extent of the target volume is subsequently photodisrupted using a femtosecond laser by moving a focus of the laser in a direction opposite the direction of propagation of the laser and then scanning the laser in multiple directions defining an subsequent treatment plane. Photodisruption is repeated at different subsequent depths until tissue at the proximal extent of the target volume is photodisrupted.

Surgical system and procedure for treatment of the trabecular meshwork and Schlemm's canal using a femtosecond laser

Systems and techniques for laser surgery are described. Scan data may be created by determining a coordinate of the object at a set of points along an arc by the imaging system, wherein the coordinate of the object is a Z coordinate of an object layer. An object shape parameter and position parameter may be determined based on the scan data by a system control module by extracting an amplitude and a phase of the scan data determining a center of the object layer based on the extracted amplitude and phase.

Optical coherence tomography (OCT) imaging surgical target tissue by nonlinear scanning of an eye

Techniques and apparatus for selectively producing half-depth and full-depth OCT images, based on a swept-source OCT interference signal. An example method comprises selecting from a first sampling rate and a second sampling rate, the second sampling rate being twice the first sampling rate, and sampling the swept-source Optical Coherence Tomography (OCT) interference signal at the selected sampling rate, using a k-clock signal having a frequency range corresponding to the first sampling rate, to produce a sampled OCT interference signal. The method further comprises processing the sampled OCT interference signal to obtain an OCT image, such that the resulting OCT image is a half-depth image in the event the first sampling rate is selected and a full-depth image in the event the second sampling rate is selected.

Dynamic mode switching for multi-mode ophthalmic optical coherence tomography

System and method of photoaltering a region of an eye using a high resolution digital image of the eye. The system includes a laser assembly for outputting a pulsed laser beam, an imaging system for capturing a real-time high resolution digital image of the eye and displaying the digital image of the eye, a user interface receiving at least one laser parameter input, and a controller coupled to the laser assembly, imaging system, and user interface. The controller directs the laser assembly to output the pulsed laser beam to the region of the eye based on the laser parameter input.

Ophthalmic laser apparatus, system, and method with high resolution imaging

A surgical system includes a laser source to generate a first set of laser pulses; a guiding optic to guide the first set of laser pulses to a target region; a laser controller to generate an electronic representation of a target scan pattern, and to control the guiding optic to scan the first set of laser pulses according to a portion of the target scan pattern to create a first photo-disrupted region in the target region; and a OCT imaging system to generate an image of a portion of the first photo-disrupted region. The laser controller can generate an electronic representation of a modified scan pattern in relation to the image generated by the SS-OCT imaging system, and control the guiding optic to scan a second set of laser pulses according the modified scan pattern.

Image processor for intra-surgical optical coherence tomographic imaging of laser cataract procedures

A cataract surgical system includes a laser source to generate a first set of laser pulses; a guiding optic to guide the first set of laser pulses to a target region in an eye; a laser controller to generate an electronic representation of a target scan pattern, and to control the guiding optic to scan the first set of laser pulses according to a portion of the target scan pattern to create a first photo-disrupted region in the target region; and an Optical Coherence Tomographic (OCT) imaging system to generate an image of a portion of the first photo-disrupted region. The laser controller can generate an electronic representation of a modified scan pattern in relation to the image generated by the OCT imaging system, and control the guiding optic to scan a second set of laser pulses according the modified scan pattern.

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San Clemente, CA, United States of America

Guy Holland