Sterling Drug Inc.

Sterling Winthrop Inc.

Viropharma Incorporated

Sanofi

Sanofi Sa

Sanofi Pharmaceuticals, Inc.

Guy D Diana

Thomas R Bailey

Theodore John Nitz

David J Aldous

Philip M Carabateas

Joseph C Collins

Gee-Hong Kuo

Dorothy C Young

William P Gorczyca

Royal A Cutler

Michael Reuman

William B Hinshaw, Jr

John Swestock

Tandy D Goldstein

A compound produced by the process comprising the step of reacting a starting compound of the formula:

Compounds, compositions and methods for treating influenza

Derivatives of piperidine are useful in prophylaxis and treatment of hepatitis C virus infections.

Compounds, compositions and methods for treatment of hepatitis C

Compounds of the formula: ##STR1## wherein R1 represents a lower alkyl (C1-C6) substituent which may be straight or branched; R2 represents an aryl substituent of the formula: ##STR2## and Q, V, W, X, Y and Z are as set forth in the accompanying specification, are useful in prophylaxis of influenza virus infection.

Compounds of the formula ##STR1## wherein Azo is alkyltetrazolyl or is chosen from the group consisting of oxadiazolyl, imidazolyl, pyrazolyl, triazolyl, oxazolyl, triazinyl, thiazolyl, isothiazolyl or any of these substituted with a member of the group consisting of alkyl, alkylthio, alkoxy, hydroxy, halo, cyano, nitro, hydroxyalkyl, alkoxyalkyl, alkoxycarbonyl, alkanoyl, fluoroalkyl or the N-oxide of any of the preceding;

Therapeutic phenoxyalkylazoles and phenoxyalkylazines

A compound of the formula: ##STR1## wherein R.sub.1 represents a lower alkyl (C.sub.1 --C.sub.6) substituent which may be straight or branched; R.sub.2 represents an aryl substituent of the formula: ##STR2## and Q, V, W, X, Y and Z are as set forth in the accompanying specification. These compounds are useful in prophylaxis and treatment of influenza virus infection.

Compounds compositions and methods for treating influenza

Compounds of the formula; ##STR1## wherein: Thi is thiadiazolyl or substituted thiadiazolyl alkoxy, fluoromethyl, difluoromethyl, trifluoromethyl, 1,1-difluoroethyl, halo, alkyl, cycloalkyl, hydroxyalkyl, or

Thiadiazoles and their uses as antipicornaviral agents

Compounds of the formula ##STR1## wherein Pyr is chosen from the group consisting of pyridyl, pyrazyl, pyrimidyl, quinolyl, indolyl and 7-azaindolyl or any of these substituted with one or two substitutents chosen from alkyl, alkoxy, hydroxy, halo, cyano, nitro, hydroxyalkyl, alkoxyalkyl, alkanoyl, fluoroalkyl or the N-oxide of any of these;

Therapeutic phenoxyalkylheterocycles

Described herein are compound of the formula: ##STR1## wherein: Thi is thiadiazolyl or substituted thiadiazolyl;

Thiadiazoles and their use as antipicornaviral agents

Substituted pyrazole dimers are useful in prophylaxis and treatment of influenza virus infections.

Pyrazole dimers compositions and methods for treating influenza

Compounds of the formula ##STR1## wherein: R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined in the specification,

Therapeutic phenoxyalkylpyridazines and intermediates therefor

Described herein are compounds of the formula; ##STR1## wherein: Thi is a unsubstituted or substituted thiadiazolyl;

Heterocyclic substituted carboxamides are useful in prophylaxis and treatment of hepatitis C virus infections.

Growing community of inventors

Stephentown, NY, United States of America

Guy D Diana