Akzo N.v.

Gustav Duweg

Michael Diamantoglou

Wolfgang Ansorge

Angelika Reiche

Thomas Rintelen

Lothar Steinfeld

Ralf Tatas

Edmund Richter

A dialysis membrane in the form of a hollow fiber with a continuous internal cavity is made of cellulose acetate or a cellulose acetate derivative. The membrane has a maximum screen coefficient of 0.04 for albumin with a molecular weight of 68,000. A dialysis membrane in the form of a hollow fiber with a continuous internal cavity may be made in a process using a spinning solution containing an organic carboxylic acid and a cavity-forming liquid. Modification agents and/or water are optionally added and the solution is extruded through a spinneret suitable for the manufacture of hollow fibers. The precipitation of the resultant dialysis membrane and the usual further aftertreatment take place in a precipitation bath. The organic carboxylic acid preferably is acetic acid and the precipitation bath preferably is a dilute acetic acid.

Process for manufacturing cellulose acetate membranes

A process for improving the biocompatibility of cellulosic film membranes is characterized by the fact that the film membranes are coated during or after their preparation with cellulose ethers and/or cellulose esters and/or cellulose carbamates whose structures conform to the formulas ##STR1## wherein Cell is the skeleton of the unmodified cellulose molecule without hydroxyl groups; x conforms to the degree of modification, which is in the range of 0.002 to 3; R is an (optionally substituted) alkyl and/or alkenyl and/or aryl and/or arylalkyl group and the carbon chain of the group R contains 1 to 36 carbon atoms and may be interrupted by hetero atoms such as O, S, N, and contains basic and/or acidic groups such as 13 NR'.sub.2, --COOR', and/or --SO.sub.3 R' or their salts, wherein R'=H or R.

Method for coating cellulosic membranes

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Wuppertal, Germany

Gustav Duweg