Aktiebolaget Hassle

Gustav B Samuelsson

Enar I Carlsson

Bo T Lundgren

Kjell I Wetterlin

Nils H Persson

Axel K Aberg

This invention relates to novel compounds of the general formula ##STR1## Representative compounds within the scope of the invention are ##STR2## The compounds are disclosed as being useful for treating symptoms and signs of cardiac failure by stimulating the .beta.-receptors of the heart. Methods of treatment using these compounds are discussed.

Heart active compounds and methods of use

Amines of the formula I ##STR1## method of preparing the same and pharmaceutical compositions and method for treating cardiovascular disorders by blocking the .beta.-receptors of the heart in combination with a peripheral vasodilating activity.

.beta.-Receptor blocking compounds and treatment of cardiovascular

Heart active compounds

An amine of the formula I set forth below ##STR1## and a method for the preparation thereof and treating cardiovascular diseases to exert its .alpha.-receptor blocking activity.

Amide substituted phenoxy propanol amines

Amines of the formula I ##STR1## method of preparing the same and pharmaceutical compositions and methods for treating cardiovascular disorders by blocking the .beta.-receptors of the heart in combination with a peripheral vasodilating activity.

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Molnlycke, Sweden

Gustav B Samuelsson