Zeltiq Aesthetics, Inc.

Gurvinder Singh Nanda

George Frangineas, Jr

Leonard C DeBenedictis

Bryan Jon Weber

Kristine Tatsutani

Peter Yee

Linda Pham

Kerrie Jiang

Treatment systems, methods, and apparatuses for treating acne, hyperhidrosis, and other skin conditions are described. Aspects of the technology can include cooling a surface of a patient's skin and detecting changes in the tissue. The tissue can be cooled a sufficient length of time and to a temperature low enough to affect glands or other targeted structures in the skin.

Treatment systems and methods for affecting glands and other targeted structures

Systems and methods that enable tissue cooling applications and delivery of electrical energy to adipose tissue for alteration and reduction of body fat are described herein. Aspects of the disclosure are directed to, for example, temperature-controlled electroporation of subcutaneous lipid-rich cells. Additional aspects of the disclosure are directed to treatment methods for treating a target region of a human subject's body to achieve an alteration of subcutaneous adipose tissue. The method can include, for example, removing heat from the target region of the human subject during a treatment process to cool subcutaneous lipid-rich cells in the target region to a temperature below normal body temperature. Furthermore, the method can include delivering energy to the target region to produce an electric field in an amount sufficient to create pores in membranes of the subcutaneous lipid-rich cells that have been cooled to the temperature below normal body temperature.

Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue

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Fremont, CA, United States of America

Gurvinder Singh Nanda