Agency for Science, Technology and Research

Pba Systems Pte Ltd.

Guolin Xu

Jackie Yi-Ru Ying

Rensheng Deng

Yoke San Daniel Lee

Zhiqiang Gao

Fang Xie

Eng Hock Francis Tay

Tseng-Ming Hsieh

Min Hu

Howe Yuen Lim

Xiaojun Chen

Chai Meng Goh

Emril Mohamed Ali

Yuan Hong Yu

Mohamed Shariff Mohamed Arshad

Lin Kiat Saw

Dor Ngi Ting

Mo-Huang Li

Hock Ming Jeremy Loh

Pei-Lin Mao

Jackie Y Ying

Eng Hock Tay

A liquid sensor for a diaper, and method of manufacturing the same are provided. The liquid sensor includes a plurality of electrochemical cells in series connection. Each of the plurality of electrochemical cells includes an anode, a cathode and a liquid-porous layer including an electrolyte solution. The liquid-porous layer electrically connects the anode to the cathode such that each cell has a respective predetermined potential difference across the cell. Two or more of the plurality of electrochemical cells are operable to be electrically connected by a liquid to form a single electrochemical cell having a potential difference lower than the sum of the predetermined potential differences of the two or more electrochemical cells.

Liquid sensor for a diaper and method of manufacturing the same

There is provided a microfluidic device comprising: a plurality of wells, each well comprising one opening to function as an inlet and an outlet for the well, wherein each opening is in fluid communication with a common fluidic channel, and wherein each opening is connected to the common fluidic channel via an isolation channel, and wherein the plurality of wells is arranged on the device in a radially symmetrical pattern. There is also provided a system and method comprising the device.

Microfluidic device

Various embodiments provide an apparatus for a diaper. The apparatus has two electrodes and an electronic device. The electronic device is coupled to the two electrodes. The two electrodes are operable to generate a potential difference when they are electrically connected together by ionized liquid. The electronic device is operable to generate an alarm signal when the potential difference is generated. Various other embodiments relate to a corresponding system, diaper and method of manufacturing an electrode.

Apparatus for a diaper, a system, a diaper and a method of manufacturing an electrode

According to various embodiments, a reagent fluid dispensing device may be provided. The reagent fluid dispensing device may include a chamber for receiving a reagent fluid, the chamber having a first opening and a second opening; a first fluid conduit connected to the first opening of the chamber; a reservoir connected to the first fluid conduit, the reservoir having a first opening, wherein the first opening of the reservoir is connected to the first fluid conduit to form a passive valve, wherein the reservoir is dimensionalized for storing a predetermined volume of the reagent fluid; and a pneumatic conduit connected to the second opening of the chamber, wherein selective application of pneumatic pressure to the chamber through the pneumatic conduit transfers the reagent fluid from the reservoir to the chamber through the first fluid conduit. According to various embodiments, a microfluidic device including the reagent fluid dispensing device, and a method of dispensing a reagent fluid may be provided.

Reagent fluid dispensing device, and method of dispensing a reagent fluid

A micro-fluidic device comprises a body. The body defines pneumatic ports, chambers for receiving liquids, and a connecting conduit. Each port is sealed with a seal and is shaped to couple to a pneumatic conduit through the seal. At least some of the chambers each have a top opening and a bottom opening. The top openings are in fluid communication with corresponding ports. The bottom openings are in fluid communication with one another through the connecting conduit, which is above the bottom openings. Selective application of pneumatic pressures to the chambers through the pneumatic conduits can transfer a liquid from one chamber to another through the connecting conduit, for example, for processing bio-samples within the device.

Fluid processing and transfer using inter-connected multi-chamber device

A microfluidic separation system, which comprises a magnetic separator, which itself comprises a magnetic energy source; first and second magnetically conductive members leading from the magnetic energy source and having respective terminal ends that are separated by a gap over which a magnetic field is applied due to the magnetic energy source. The separation system further comprises a microfluidic chip for insertion into the gap, which comprises a body defining channels on respective faces of the body; and an exterior lining that seals the plurality of channels to allow separate test sample volumes to circulate in at least two of the channels. Upon insertion of the chip into the gap, a first test sample volume is confined to circulating closer to the terminal end of the first member and a second test sample volume is confined to circulating closer to the terminal end of the second member.

Microfluidic separation system

A device for sample tissue disruption and/or cell lysis comprising: a piezoelectric material; and at least a second material in contact with the piezoelectric material; and wherein the second material has an uneven surface on an opposite side to that in contact with the piezoelectric material. The device may be made by assembling at least three layers and membranes for the valves and pumps. The piezoelectric material is actuated by an external voltage source to generate cavitation, which disrupts tissue and/or lyses cells, in particular by a modulated alternative external voltage. The invention further provides a method of disrupting tissue and/or lysing cells in a device. Also provided is a piezoelectric device comprising a piezoelectric material in contact with a second material, and wherein the second material has an uneven surface on an opposite side to that in contact with the piezoelectric material.

Method and device for the treatment of biological samples

An electrically non-conductive, nanoparticulate membrane comprising nanoparticles of at least one inorganic oxide of an element selected from Group IA, IIA, IIIA, IVA, IB, IIB, IIIB, IVAB, VB, VIB, VIIB or VIIIB of the Periodic Table, and wherein an oxidoreductase enzyme and a polymeric redox mediator capable of transferring electrons are diffusibly dispersed in said nanoparticulate membrane.

Electrically non-conductive, nanoparticulate membrane

A micro-pump having a first layer, a second layer and an intermediate flexible layer is disclosed. The first layer and second layer may be of moldable plastics. The intermediate layer may be a substantially flat PDMS membrane layer having an inlet hole and an outlet hole. The first layer and the second layer are disposed on either side of the intermediate layer to define a pumping chamber that encloses an actuatable portion of the intermediate layer and valve seats that abut the inlet hole and the outlet hole of the intermediate layer. The actuatable portion is moveable to increase and reduce the volume of the pumping chamber to allow pressure to lift the respective intermediate layer portions surrounding the inlet hole and the outlet hole to thereby draw fluid and expel fluid from the pumping chamber respectively.

Micro-pump

An integrated coil assembly ( ), a multi-phase linear motor having the integrated coil assembly ( ) and a method ( ) for forming the integrated coil assembly ( ) are described. The integrated coil assembly ( ) has multi-phase coils with each multi-phase coil ( ) having a number of coil loops based upon the number of electrical phases of current required by the multi-phase linear motor. The coil loops of different multi-phase coils are interweaved at two opposing portions ( ) and are substantially parallel at two other opposing portions ( ). In the method ( ), different wire dispensers wind coil loops for different electrical phase for each multi-phase coil ( ). However, the same wire dispenser winds coil loops that are for the same electrical phase for different multi-phase coils ( ). The coil loops for each multi-phase coil ( ) are wound before the coil loops of another multi-phase coil ( ) are wound.

Growing community of inventors

Singapore, Singapore

Guolin Xu