Sun Yat-sen University Cancer Center

Guokai Feng

Jun Wang

Musheng Zeng

Mengqing Zhang

Xing Zhang

Qian Zhong

A tumor-targeting peptide is disclosed. This tumor-targeting peptide comprises a typical motif with the general formula of: XX(Y/F) (D/E) (D/E) XX. The motif is selectively connected with 1-3 amino acids at the C-terminal and/or N-erminal. X represents any one of the twenty natural amino acids or the D type amino acids. The present invention also discloses that the peptide can not only target tumor vessels and tumor cells but also penetrate them and thus can be applied in tumor diagnosis and therapy.

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Guangzhou, China

Guokai Feng