Boehringer Ingelheim Pharmaceuticals, Inc.

Karl Thomae Gmbh

Gunther Trummlitz

Wolfgang Eberlein

Wolfhard Engel

Karl D Hargrave

Gunther Schmidt, Deceased

John Robert Proudfoot

Karl G Grozinger

Julian Adams

Gerhard Mihm

Norbert Mayer

Adriaan De Jonge

Disclosed are novel 5,11-dihydro-6H-dipyrido[3,2-b; 2',3'-e][1,4]diazepines. These are useful in the prevention or treatment of HIV infection.

5,11-dihyro-6H-dipyrido[3,2-B:2',3'-e][1,3]diazepines and their use in

Disclosed are novel pyridodiazepines. These compounds, as well certain known 6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-ones are useful in the treatment of AIDS, ARC and related disorders associated with HIV infection.

The treatment of HIV-1 infection using certain pyridodiazepines

5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in

Novel condensed diazepinone of general formula I are described, ##STR1## wherein B represents one of the divalent groups ##STR2## and X.sup.1, X.sup.2, A.sup.1, A.sup.2 and R.sup.1 to R.sup.10 are as defined in herein useful as vagal pacemakers for treating bradycardia and bradyarrhythmia. The novel diazepinones also have spasmolytic properties on peripheral organs, antiemetic properties and are capable of promoting cerebral blood flow.

Condensed diazepinones, processes for preparing them and pharmaceutical

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Warthausen, Germany

Gunther Trummlitz