Carl Zeiss Microscopy Gmbh

Carl Zeiss Ag

Cad Zeiss Jena Gmbh

Gunther Lorenz

Ingo Kleppe

Ralf Netz

Yauheni Novikau

Christoph Nieten

Joerg Steinert

Mario Sondermann

Michael Gölles

Torsten Antrack

Oliver Holub

An optical arrangement includes a stack structure comprising at least three prisms. The optical arrangement includes a main optical path and for each of the prisms, a secondary optical path. The optical arrangement also includes at least one interface. Each of the at least one interface is arranged between a corresponding first stack section of the stack structure and a corresponding second stack section of the stack structure. Each of the at least one interface is configured to enable relative movement of the corresponding first stack section and of the corresponding second stack section with respect to one another.

Multi-way prism

Microscope and method for high resolution scanning microscopy of a sample, wherein

High-resolution scanning microscopy

As a result of the size of the detector elements thereof, optoelectronic detectors such as photoelectron multipliers comprising a light-entry region sealed by a protective disc can only be used with much outlay for recording an image of a diffraction-limited focus volume in a two-dimensional spatially resolved manner, even if the image is significantly magnified in relation to the focus volume. The novel detector is intended to enable the spatially resolved detection of point spread functions with little outlay and high accuracy. 2.2 For this purpose, a body made of glass or glass ceramics comprising an opening, in which one end of an optical fiber is arranged, is cemented to the cover disc in such a way that the end of the optical fiber faces the cover disc and the optical axis thereof intersects the light-entry region. Thus, the relative position of optical fiber and entry region can be provided permanently with high accuracy. Preferably, the detector includes a plurality of detection channels, in particular 32 channels, comprising a respective light-entry region and the body includes a plurality of openings comprising a respective optical fiber. 2.3 Fluorescent microscopy.

Optoelectronic detector, in particular for high-resolution light scanning microscopy

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Jena, Germany

Gunther Lorenz