Katholieke Universiteit Leuven

Katholieke Universiteit Leuven, Ku Leuven R&d

Gunter Carlens

Arnaud Marchand

Johan Neyts

Kai Dallmeier

Dorothée Bardiot

Mohamed Koukni

Suzanne Kaptein

Wim Smets

Michael McNaughton

Patrick Chaltin

Zeger Debyser

Frauke Christ

Marc De Maeyer

Damien Marchand

Arnout Voet

The present invention relates to a series of novel compounds, methods to prevent or treat viral infections in animals by using the novel compounds and to said novel compounds for use as a medicine, more preferably for use as a medicine to treat or prevent viral infections, particularly infections with RNA viruses, more particularly infections with viruses belonging to the family of the Flaviviridae, and yet more particularly infections with the Dengue virus. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the novel compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of viral infections. The invention also relates to processes for preparation of the compounds.

Viral replication inhibitors

The present invention relates to a series of novel compounds, methods to prevent or treat viral infections in animals by using the novel compounds and to said novel compounds for use as a medicine, more preferably for use as a medicine to treat or prevent viral infections, particularly infections with RNA viruses, more particularly infections with viruses belonging to the family of the Flaviviridae, and yet more particularly infections with the Dengue virus. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the novel compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of viral infections. The invention also relates to processes for preparation of the compounds. 

Growing community of inventors

Leuven, Belgium

Gunter Carlens