Bayer Aktiengesellschaft

Gunter Benz

Karl G Metzger

Delf Schmidt

Jorg Pfitzner

Hans-Joachim Zeiler

Theo Schroder

Horst Weyland

Johannes-Peter Stasch

Andreas Knorr

Wolfgang Bender

Rolf Henning

Renin-inhibiting aminomethyl peptides of the formula ##STR1## in which A is H, an alkyl radical, a sulphony radical or an amino-protecting group,

Aminomethyl peptides

Renin-inhibiting aminomethyl peptides of the formula ##STR1## in which A is H, an alkyl radical, a sulphonyl radical or an amino-protecting group,

Renin-inhibiting peptides having an aminomethyl side chain

New antibiotics of the formula ##STR1## in which X is O or N--CO--NH.sub.2,

New antibiotics, preparation and use of and intermediates therefor

Antibiotics, preparation and use of and intermediates therefor

An antibiotic compound which can be in the iron-free or iron-containing form and has the structural formula (B) as described herein. The compound possesses antimicrobial activity. Also fermentation processes for preparation of the above-mentioned antibiotic compound. In addition, pharmaceutical compositions containing said antibiotic compound and the use of said antibiotic compound and compositions for combating bacterial infection.

Streptomyces species and process for producing antibiotic

The invention relates to compounds of the formula ##STR1## said compounds being obtainable by cleavage of compounds of formula ##STR2## The compounds of the invention as well as compositions and medicaments containing a compound of the invention are useful as antimicrobial agents.

Cleavage products of 4',6'-didesoxy-4'-thio-,6'-amino-hepturonic acid

The invention relates to antimicrobial compounds of Formula (I) and semi-synthetic methods for their production. Also included in the invention are compositions containing said antimicrobial compounds and methods for the use of said compound and compositions.

Antibiotic compounds, their production and their medicinal use

The invention relates to an antibiotic compound which can be in the iron-free or iron-containing form and has the structural formula (A) as described herein. The compound possesses antimicrobial activity. Also included in the invention are fermentation processes for preparation of the above-mentioned antibiotic compound. In addition, the invention includes pharmaceutical compositions containing said antibiotic compound and the use of said antibiotic compound and compositions for combating bacterial infections.

Antibiotic compound, its production and its medicinal use

The invention relates to an antibiotic compound which can be in the iron-free or iron-containing form and has the structural formula (B) as described herein. The compound posesses antimicrobial activity. Also included in the invention are fermentation processes for preparation of the above-mentioned antibiotic compound. In addition, the invention includes pharmaceutical compositions containing said antibiotic compound and the use of said antibiotic compound and compositions for combating bacterial infection.

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Velbert, Germany

Gunter Benz