Evestra, Inc.

Gulzar Ahmed

Klaus Nickisch

Hareesh Nair

Frederick Meece

Walter Elger

Ralf Wyrwa

Bindu Santhamma

Described herein are progestin compounds that have extended release rates and that can be used without an estrogen to produce a contraceptive state.

Longer-acting progestin prodrug contraceptives

Various prodrug compounds having the general structure: Active agent&#x2014;(acid)-(linker)&#x2014;SONRRare described herein. Compounds having this general structure were shown to be more orally active than the unmodified parent molecule.

Pro-drug forming compounds

Various prodrug compounds having the general structure: Active agent-(acid)-(linker)-SONRRare described herein. Compounds having this general structure were shown to be more orally active than the unmodified parent molecule.

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San Antonio, TX, United States of America

Gulzar Ahmed