Vitafin N.v.

Guillaume L Cals

Frederik H Wittkampf

Kornelis A Mensink

Hendrik L Brouwer

A physiological stimulating system includes improved means for minimizing the polarization that results at the stimulus site, thereby enabling enhanced detection of evoked responses. In the pacemaker embodiment, the stimulus signal comprises positive recharge pulses immediately before and immediately after the negative stimulus signal, the recharge pulses being adapted in a time duration and amplitude such that the total current delivered to the stimulus site, (e.g., a patient's heart) by the stimulus signal is substantially zero.

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Dieren, Netherlands

Guillaume L Cals