Mimedx Group, Inc.

Spinemedica, LLC

Carticept Medical, Inc.

Guilhem Denoziere

Daniel Tomko

Thomas J Koob

Anish Ghodadra

Stephan Eckhof

Randal R Betz

David N Ku

John W McClellan

Rebeccah J C Brown

Barbara D Schweizer

Rebeccah Brown

Rebeccah Jc Brown

Matthew Miller

Alexander Geisser

Rebeccah JC Brown

Described herein are molded dehydrated placental tissue compositions, and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the molded dehydrated placental tissue compositions are also described herein.

Molded placental tissue compositions and methods of making and using the same

Spinal disc and other implants include at least one flexible keel that extends substantially outwardly, typically upwardly or downwardly, beyond the primary body of the implant. Methods of fabricating elastomeric implants using a mold are also described.

Spinal disc implants with flexible keels and methods of fabricating implants

Methods for forming molded orthopedic implants with at least one mesh substrate having opposing upper and lower primary surfaces. At least a major portion of the mesh substrate lower primary surface is integrally moldably attached to the molded implant body. The methods are carried out so that the mesh substrate has at least one selectively exposed region devoid of molded material that exposes at least a portion of the mesh substrate upper surface to at least a partial thickness of the mesh substrate so as to allow for tissue in-growth in the at least one exposed region of the mesh substrate.

Methods for forming implants with selectively exposed mesh for fixation and related implants

Methods and systems for generating custom implants by programmatically analyzing a patient's image data to electronically obtain shapes and dimensions of relevant anatomical features of a target region of the patient; and fabricating a patient-specific replacement implant for the patient using the analyzed patient image data. Related patient-specific spinal implants are also described.

Patient-specific spinal implants and related systems and methods

Trials for spinal surgery include: (a) a trial implant portion having a shape corresponding to an implantable spinal disc implant; (b) a shaft connected to the trial implant portion; and (c) at least one axially extending cutting guide slot attached to the shaft at a position that is axially spaced apart from the trial implant portion, the cutting guide slot configured to releasably slidably receive and guide a cutting blade toward vertebral bone. Also described are additional surgical instruments, including, for example, pilot-hole punches, inserters, and methods of cutting keelways.

Surgical instruments for spinal disc implants and related methods

Methods of fabricating elastomeric implants employ a mold with PVA crystals and irrigant added to the mold independent of each other. Related molds are also described.

Methods of producing PVA hydrogel implants and related devices

Molded orthopaedic implants include at least one mesh substrate having opposing upper and lower primary surfaces. At least a major portion of the mesh substrate lower primary surface is integrally moldably attached to the molded implant body. The mesh substrate has at least one selectively exposed region devoid of molded material that exposes at least a portion of the mesh substrate upper surface to at least a partial thickness of the mesh substrate so as to allow for tissue in-growth in the at least one exposed region of the mesh substrate.

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Atlanta, GA, United States of America

Guilhem Denoziere