Bayer Aktiengesellschaft

Ciba-geigy Ag

Kramer Aktiengesellschaft

Bayer Akitnegesellschaft

Guido Steffan

Franz-Josef Mais

Alexander Klausener

Horst Behre

G&uuml;nther Cramm

Helmut Fiege

Albrecht Marhold

Nikolaus Muller

Joachim Komoschinski

Lutz Heuer

Stefan Antons

Mark Robert Fisher

Erich Wolters

John Charles DeBraal

Axel Vogel

Gunther Cramm

Peter P Wenzl

Reinhard Kaiser

Georg Hardenbicker

Heinz U Blank

Karlfried Wedemeyer

Wolfgang Harms

Reinhold M Klipper

Ernst Kysela

Hans Lindel

Walter Lange

Alfred Mitschker

Holger Lutjens

Rolf Putter

Klaus-Christian Paetz

Bernhard Beitzke

Werner Struver

Guido Giffels

Otto Neuner

Arnd Stuwe

Viktor Trescher

Friedrich Durholz

Bernd Griehsel

Karl Mannes

Andreas Sattler

Thomas Essert

Heinrich Pelster

Bernhard Albrecht

Jurgen Zander

Wolfgang Schenk

Bruno Kruger

Otto Lindner

Karl-Wilhelm Henneke

Volker Kass

Hans-Joachim Becker

Michael Herzhoff

Wulf K&uuml;hnle

Otto Barth

Vinzenz Habermacher

Hans Frey

Lutz Kienitz

Ernst Borgmann

Peter Buchel

Albert Hullen

The present invention relates to a process for preparing 4,6-dichloropyrimidine by reaction of 4-chloro-6-hydroxypyrimidine with an acid chloride.

Method for producing 4,6-dichloropyrimidine

The present invention relates to a process for preparing 4-chloro-6-hydroxypyrimidine from 4-chloro-6-methoxypyrimidine.

Method for producing 4-chloro-6-hydroxypyrimidine

Method for producing 4,6-dichloropyrimidine with sulfur compounds and phosphorus compounds

Process for converting a nitrobenzene into a free aminophenol by catalytic reduction hydroxylation in the presence of an aqueous-acidic reaction medium.

Process for converting nitrobenzene to a free aminophenol

The invention relates to substituted cinnamic acids and cinnamic acid esters of formula (I), wherein X represents F, Cl or J and R and R are the same or different and represent hydrogen, an optionally substituted C -C -alkyl radical or an optionally substituted benzyl radical. Substituted indanone carboxylic acid esters are produced using said substituted cinnamic acid and cinnamic acid ester in a technically simple and non-dangerous manner as far as safety is concerned.

Substituted cinnamic acids and cinnamic acid esters

The invention relates to a method for the preparation of 4,6-dichloropyrimidine by reacting 4-chloro-6-methoxypyrimidine with phosgene as chlorinating agent in the presence of a nitrogen-containing auxiliary.

Method for the production of 4,6-dichloropyrimidine with the aid of phosgene

The present invention relates to a process for preparing 4,6-dichloro-pyrimidine by reaction of 4-chloro-6-methoxypyrimidine with an acid chloride in the presence of a hydrogen halide.

Method of producing 4,6-dichloropyrimidine with acid chlorides

2-Halogenoindan-1-ones are prepared in an advantageous manner by converting anilines into diazonium salts and these, with acrylic compounds, into 3-phenyl-1-halogenoproprionic acid derivatives, and latter are cyclized.

Process for preparing 2-halogenated indan-1-ones

Method of preparing 4,5,6-trichloro-and 2,4,5,6-tetrachloropyrimidine

In a particularly advantageous process for producing 2-cyanoindan-1-ones from 2-halogenated indan-1-ones by reaction with a cyanide salt, the cyanide salt is dissolved in a dipolar aprotic solvent or in a water-miscible ether and 2-halogenated indan-1-one is metered into this solution.

Process for preparing 2-cyanoindan-1-ones

Grignard reagents which contain a protected aldehyde function are obtained in a particularly advantageous manner from a halogenated aldehyde by reaction with a secondary monoamine to give an open-chain aminal, and conversion of the latter into a Grignard reagent using metallic magnesium. The invention also relates to novel Grignard reagents of this type.

Process for the preparation of Grignard reagents and novel Grignard reagents

The invention discloses a novel thermally-responsive record material comprising a support having coated thereon a thermally sensitive color forming composition comprising a chromogenic material, an acidic developer material and a certain carbamate component that does not include dodecyl-N-phenylcarbamate. The novel record material displays enhanced image intensity or improved thermal response.

Thermally-responsive record material

The process according to the invention can be illustrated by way of example by the following equation:

Method for the production of 2,6-dichloro-5-fluoronicotinonitrile and the chemical compound 3-cyano-2-hydroxy-5-fluoropyride-6-one-monosodium salt its tautomers

Acetophenones which are substituted on the aromatic ring by fluoroalkyl are prepared in a particularly advantageous, environmentally friendly and effective manner from fluoroalkylanilines and acetaldoxime by preparing from a fluoroalkylaniline a corresponding diazonium salt solution, and reacting this with acetaldoxime in the presence of at least one copper compound, without adding any buffer salts or reducing agents, carrying out the reaction at from 20 to 50&deg; C. and in the presence of halide ions and subsequently heating to a temperature in the range from 70 to 110&deg; C.

Method for preparing acetophenones with a fluoralkyl-substituted aromatic nucleus

Method of preparing 4,5,6-trichloro- and 2,4,5,6-tetrachloropyrimidine

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Odenthal, Germany

Guido Steffan