Other

Indena S.p.a.

Universitá Degli Studi Di Torino

Guido Forni

Federica Cavallo

Augusto Amici

Cristina Marchini

Elena Quaglino

Roberto Chiarle

Giorgio Inghirami

Emilio Hirsch

Elisa Ciraolo

Claudia Curcio

Use of intracytoplasmatic domain of Anaplastic Lymphoma Kinase (ALK) protein and/or a nucleic acid molecule encoding for the intracytoplasmatic domain of Anaplastic Lymphoma Kinase (ALK) protein, of any species, for the preparation of a medicament, preferably a vaccine, for the treatment and/or prevention of a tumor in a subject, preferably a lymphoma.

Anaplastic lymphoma kinase (ALK) as oncoantigen for lymphoma vaccination

Methods for inhibiting the formation and growth of a p185positive tumor in a subject, and for treating a subject having a p185positive tumor, utilizing a DNA vector coding for a chimeric rat/human Her-2/neu/ErbB-2 protein are provided.

[object Object]

Plasmids containing sequences encoding different fragments of p185oncoprotein, able to induce an immune response against tumours expressing oncogenes of the ErbB family, and pharmaceutical compositions thereof.

DNA plasmids containing sequences coding for different fragments of 185oncoprotein which are able to induce an immune response against p185-overexpressing tumors, and pharmaceutical compositions thereof are described.

We describe the use of PI3K&#x3b2; protein and/or its encoding gene for the screening for substances useful in the treatment of cancers, preferably breast cancers, as well as a method for the diagnosis of malignant cell growth comprising the measuring the expression of PI3K&#x3b2;. We also describe non-human transgenic animals as models for studying human pathologies, preferably breast cancer, being transgenic for having altered PI3K&#x3b2; and Neu-T expression.

Growing community of inventors

Turin, Italy

Guido Forni