Hoffmann-La Roche Inc.

Genentech, Inc.

F. Hoffmann-La Roche Ag

Guido Drees

Neil Bentley Cammish

Monica De Bardi

Maria Enterrios Quintana

Nariye Salibryam Cavusoglu Ataman

Joseph Alexander Martin

Holger Roehl

Thomas Peter Stuedeli

Eszter Voros

Marcel Sigrist

Shreya Munjal

Matthieu Noël Claude Giletti

A closure system is disclosed for closing a container opening. The closure system includes a stopper member, a cage member for mounting to the container, and a spring member. The stopper member has a plug portion that tightly fits into the container opening and a cover portion that abuts a boundary surface adjacent to the container opening container. The stopper member plug portion is fitted into the container opening, the stopper member cover portion abuts the boundary surface of the container, and the cage member is mounted to the container to hold the stopper member, when the closure system is in an assembled state. The cage and spring members are arranged to position the spring member between the stopper member cover portion and the cage member such that the spring member pushes the cage member away from the cover portion when the closure system is in the assembled state.

Closure system and kit

A closure system for closing a container opening is disclosed that includes a stopper member, a cage member for mounting to a container, a cover member reversibly mountable to the cage member, and an integrity visualization member. The stopper member has a plug portion to fit into the container opening and a cover portion to abut a boundary surface of the container opening. The plug portion of the stopper member is fitted into the opening of the container and the cage member is mounted to the container. The cage member applies a force to the cover portion to push the cover portion onto the boundary surface of the container opening. The cover member covers an aperture of the cage member when mounted to the cage member. The integrity visualization member indicates an integrity of the closure system and is positioned between the cover portion and the cage member.

A closure system for closing a container opening is disclosed that includes a stopper member, a cage member and a lock activation formation. The stopper member includes a plug portion to fit into the container opening and a cover portion to abut a boundary surface of the container opening. In the assembled state of the closure system, the plug portion is fitted into the container opening, the cover portion abuts the boundary surface, and the cage member is mounted to the container. The cage member has a locking structure that in a detached position is disengaged from the container, and in a fixed position engages a corresponding structure of the container. The lock activation formation is configured to interact with the cage member such that the cage member changes from the detached position to the fixed position.

Growing community of inventors

Basel, Switzerland

Guido Drees