Roche Diagnostics Operations, Inc.

Roche Molecular Systems, Inc.

Hitachi High-tech Corporation

Carl Freudenberg Kg

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Guenter Ziegler

Peter Wenzig

Yoshihiro Yamashita

Koshin Hamasaki

Takaaki Hagiwara

Hermann Leying

Michaela Windfuhr

Norbert Franken

Yuichiro Ota

Oliver Larbolette

Reiner Babiel

Judith Pinsl-Ober

Michael Kuehnl

Ralf Heldmann

Markus Clemens

Thomas Vess

Johannes Stoeckel

Rolf Herb

Heike Guggemos

Rouven Ratfisch

Juergen Dittrich

Juergen Mall

Busbar comprising a supporting body () made of a tough-hard material, and at least one electrical conductor (, . . . ), wherein the conductor (, . . . ) is connected to the supporting body (). The supporting body () comprises a seal () that is made of a rubber-elastic material, which encloses the conductor (, . . . ) on the outer circumferential side with an annular sealing region () in a sealing manner.

Busbar and arrangement comprising such a busbar

The object of the invention is to provide an automatic analysis apparatus capable of setting a dispensing mechanism for measuring dispensing accuracy and a dispensing volume, and capable of performing dispensing accuracy measurement without absorbance measurement. Regarding a dispensing accuracy, a dispensing mechanism to be measured is designated. Parameters including a dispensing volume and the like are input. A dispensing operation of the input dispensing volume is automatically performed for each designated dispensing mechanism. A reaction vessel contains, for example, a reagent of the input dispensing volume which has been dispensed by the designated dispensing mechanism. By measuring a weight of the reagent in the reaction vessel, or the like, it is possible to measure the dispensing accuracy of the designated dispensing mechanism.

Automatic analysis apparatus

An apparatus for processing a laboratory sample contained in a laboratory sample container is presented. The apparatus comprises an optical sensing unit for sensing a transmittance at different vertical positions through the laboratory sample container and a tip sensing unit having a tip. The tip sensing unit is adapted to provide a tip sensing signal (tLDS) depending on a position of the tip relative to the sample. The apparatus also comprises a process control unit adapted to control the secure and reliable pipetting of the laboratory sample in response to both the transmittance and the tip sensing signal (tLDS) provided by the tip sensing unit.

Laboratory automation system including improved processing of a laboratory sample by optical and tip position sensing

The invention relates to an apparatus and a method of freezing a liquid substance contained in at least one receptacle, comprising the steps of: providing the liquid substance in at least one receptacle, providing a cooling chamber and a cooling device having a cooling surface; setting the temperature of the cooling surface, starting a freezing procedure by placing the receptacle with the liquid substance therein on the cooling surface to form a seed or initial zone of nucleation; and continuing the freezing procedure to completely freeze the substance.

Directional freezing

Method and apparatus, including computer program products, implement techniques for quantifying a target nucleic acid (target) in a test sample. The techniques include providing a target and a defined initial amount of an internal control nucleic acid (control) different from the target; amplifying the target and control in a common amplification process; measuring a quantity indicating the amount of amplification product for the target and for the control in relation to a parameter representing the progress of the amplification; determining a characteristic value of the progress parameter for the target based on measurement results related to the amount of target amplification product; possibly determining a characteristic value of the progress parameter for the control based on measurement results related to the amount of control amplification product; and quantifying the original amount of target according to a predefined or selected quantification scheme using at least the characteristic value for the target.

Quantification schemes for quantifying nucleic acids

The present invention relates to a method for monitoring a fluid transfer process, including the steps: providing an allowable pressure profile; detecting a pressure occurring in the course of the fluid transfer process; comparing detected pressure with the allowable pressure profile and signaling an error, if the detected pressure is not within the allowable pressure profile. The allowable pressure profile is defined by interpolation points, the interpolation points being based on a probability function representing a family of pressure courses of a plurality of fluid transfer processes. The allowable pressure profile can be divided into at least two distinct process sections, each section corresponding to a distinct process phase of the fluid transfer process. The probability function is calculated from a family of test pressure curves and reflects the statistical behavior of the pipette system. The present invention further relates to a computer readable medium for storing interpolation point information as well as to a kit-of-parts comprising a device implementing the inventive method, together with a computer readable medium for storing interpolation point information.

Method for monitoring a fluid transfer process

The present invention provides a method, an apparatus and a computer program to detect the liquid leakage of a liquid transfer device. In particular, the present invention is directed to a method, an apparatus and a computer program that detects the liquid leakage of a liquid transfer device with electrical means.

Electrical drop surveillance

Growing community of inventors

Polling, Germany

Guenter Ziegler