Merck Patent Gmbh

Guenter Moddelmog

Roberto Ognibene

Thorsten Wedel

Finn Bauer

Dieter Lubda

Gudrun Birk

Walter Hamm

Tanino Scaramuzza

Harald Benk

James Easson

Hans-Kurt Peth

Jens Klatyk

Daniela Kleinwaechter

Michael Schleehahn

Harald Muessig

Melina Decker

Marianne Dohmen

Heike Mueller

Ralf Fiedler

The present invention relates to compacted glycine granules, where at least 75% of the granules have a particle size of above 0.7 mm, and to a process for the preparation and use of granules of this type.

Glycine particles

The present invention relates to a novel directly compressible matrix for the production of tablets which disintegrate rapidly in the presence of moisture, in particular in the mouth.

Direct injection moldable and rapidly disintegrating tablet matrix

The present invention relates to premixes for the production of active compound-containing tablets which comprise polyvinyl alcohols (PVAs). The invention also relates to active compound-containing tablets which comprise a corresponding premix.

Pulverulent, directly compressible polyvinyl alcohol grades

The present invention relates to novel pharmaceutical formulations which have controlled, delayed release of active ingredient, and to a process for the preparation of such formulations. The invention additionally relates to the use of these novel pharmaceutical administration forms as medicaments for the treatment of diseases which require delayed release of the active ingredient, such as hypertension, or asthmatic diseases.

Formulation having controlled, delayed release of active ingredient

The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (PVAs) and fine-grained microcrystalline celluloses (MCCs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.

Directly compressible composition comprising microcrystalline cellulose

The present invention relates to a highly pure, anhydrous sodium carbonate having a low pore content for use in pharmaceutical formulations and in the foods industry. Furthermore, a novel process for the preparation of this sodium carbonate is provided.

Anhydrous sodium carbonate having a low pore content

The present invention relates to a process for the preparation of a composition for the production of tablets and to a composition obtained thereby. This composition is a directly compressible composition which results both in improved tabletting properties and in improved tablet properties.

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Reinheim, Germany

Guenter Moddelmog