Novartis Ag

Gudrun Werner

Philipp Lehr

Jose M Carballido Herrera

Herbert Jaksche

Anthony Winiski

Günther Lametschwandtner

José M Carballido Herrera

Claudia Guenther

N-(benzenesulphonyl)-2,3-dihydro-1H-indols, wherein the indol is substituted by cyano, carboxy or alkylcarbonyloxy and their use as therapeutical agents.

N-arylsulfonyl-2,3-dihydro-1H-indoles and the use thereof as CCR9 inhibitors

Compounds of formula I, wherein one of Rand Ris thienyl which is substituted by halogen and the other of Rand Ris substituted phenyl, wherein the substituents are as defined in the claims, with the proviso that the phenyl group is substituted by at least a cyano, carboxy or ()alkyloxycarbonyl group, are inhibitors of CCR9 activity and useful for therapeutic treatment. 

Inhibitors of CCR9 activity

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Vienna, Austria

Gudrun Werner