Danisco US Inc.

Genencor International, Inc.

Gudrun Vogtentanz

David Aaron Estell

Scott Douglas Power

Katherine D Collier

Brian Frederick Schmidt

Richard Ray Bott

Neelam S Amin

Melodie Estabrook

Bryan P Fox

Frits Goedegebuur

Marc Kolkman

Bradley R Kelemen

Thijs Kaper

Anita Van Kimmenade

Slavko Kralj

Igor Nikolaev

Sander Van Stigt Thans

Mats Sandgren

Jeffrey V Miller

Grant C Ganshaw

Hans De Nobel

Jian Yao

James T Kellis, Jr

Benjamin S Bower

Lilia Maria Babe

Wolfgang Aehle

Sina Pricelius

Joshua Roy Basler

Louise Wallace

Miles Christopher Scotcher

Katherine Augustyn

Johannes Franciscus Thomas Van Lieshout

Michael Stoner

Adam Garske

David Marquez

Priyanka Chandrasekaran

Jonathan Caspi

Anthony G Day

Christopher James Murray

Ronaldus W J Hommes

Ronaldus Wilhelmus Hommes

Ronaldus Wilhelmus Joannes Hommes

Paulien Kruithof

Raj Lad

Johan Van Lieshout

Wilhelmus Antonious Hendricus Van Der Kley

Sander Van Stigt-Thans

Pim Van De Kley

Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

Protease variants and uses thereof

The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.

Cellulase variants with improved expression, activity and stability, and use thereof

The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants.

Beta-glucosidase I variants with improved properties

The present invention provides peptides and supported peptides for treating various diseases and conditions. In particularly preferred embodiments, the present invention provides compositions and methods for personal care. In some embodiments the present invention provides compositions for use in skin and/or hair care, as well as cosmetic compositions. IN alternative particularly preferred embodiments, the present invention provides peptides and supported peptides for treating diseases of the skin, such as rosacea. In some particularly preferred embodiments, the supported peptides of the present invention are anti-VEGF peptides. In alternative particularly preferred embodiments, the anti-VEGF peptides are expressed on a scaffold protein. In some most preferred embodiments, the scaffold protein comprises BBI.

Peptide personal care compositions and methods for their use

The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care.

Modified variant Bowman Birk Protease Inhibitors

Modified variant Bowman Birk protease inhibitors

Modified variant bowman birk protease inhibitors

The present invention relates to compositions that comprise modified variant Bowman Birk Protease Inhibitor proteins (BBPIs). The modified variant BBPIs comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses the compositions comprising the modified variant BBPIs, and the methods for making and using the compositions in personal care.

Personal care compositions comprising modified variant Bowman Birk Protease Inhibitors

The present invention provides compositions and methods related to expression of protease inhibitors and variants thereof in bacterial species. The present invention further provides fusion nucleic acids, vectors, fusion polypeptides, and processes for obtaining the protease inhibitors.

Compositions comprising bowman-birk protease inhibitors and variants thereof

The present invention provides compositions and methods related to the expression of Bowman-Birk protease inhibitors and variants thereof in bacterial species. The present invention further provides fusion nucleic acids, vectors, fusion polypeptides, and processes for obtaining the Bowman-Birk protease inhibitors.

Bacterial expression of bowman-birk protease inhibitors and variants thereof

Growing community of inventors

Sunnyvale, CA, United States of America

Gudrun Vogtentanz