Other

Shandong Luye Pharmaceutical Co., Ltd.

Shandong Danhong Pharmaceutical Co., Ltd.

Guangwen Yang

Shuhui Chen

Jian Li

Wentao Wu

Zhixiang Li

Jie Li

Fei Wang

Yang Zhang

Wei Gu

Jikui Sun

Yongbo Fang

Mingxing Teng

The present invention relates to a series of 2,6-dioxaspiro [4,5] decane derivatives and applications thereof in preparation of opiate receptor &#x3bc; agonist related drugs; and in particular relates to the derivative compounds shown in formula (I), tautomers thereof or pharmaceutically acceptable compositions thereof. 

2,6-dioxaspiro [4,5] decane derivatives and preparation method therefor and pharmaceutical applications thereof

The present invention relates to a compound shown in formula (II) or a pharmaceutically acceptable salt thereof and an application of the same in preparing a drug for treating a disease related to angiotensin II receptor type 2 (ATR).(II) 

Carboxylic acid derivative as ATR receptor antagonist

Disclosed in the present disclosure is a Dezocine analog, and particularly disclosed are compounds represented by formula (I), (II) and (III), a pharmaceutically acceptable salt or tautomer thereof. 

Dezocine analogue

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Shanghai, China

Guangwen Yang